Variable Na_v1.5 Protein Expression from the Wild-Type Allele Correlates with the Penetrance of Cardiac Conduction Disease in the Scn5a^+/− Mouse Model

• Anne-Laure Leoni,

  Affiliations INSERM, UMR915, l'Institut du Thorax, Nantes, France, Université de Nantes, Nantes, France

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• Bruno Gavillet,

  Affiliation Department of Pharmacology and Toxicology, University of Lausanne, Lausanne, Switzerland

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• Jean-Sébastien Rougier,

  Affiliation Department of Clinical Research, University of Bern, Bern, Switzerland

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• Céline Marionneau,

  Affiliations INSERM, UMR915, l'Institut du Thorax, Nantes, France, Université de Nantes, Nantes, France

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• Vincent Probst,

  Affiliations INSERM, UMR915, l'Institut du Thorax, Nantes, France, CNRS, ERL3147, Nantes, France, Université de Nantes, Nantes, France, CHU Nantes, l'Institut du Thorax, Nantes, France

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• Solena Le Scouarnec,

  Affiliations INSERM, UMR915, l'Institut du Thorax, Nantes, France, CNRS, ERL3147, Nantes, France, Université de Nantes, Nantes, France

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• Jean-Jacques Schott,

  Affiliations INSERM, UMR915, l'Institut du Thorax, Nantes, France, CNRS, ERL3147, Nantes, France, Université de Nantes, Nantes, France, CHU Nantes, l'Institut du Thorax, Nantes, France

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• Sophie Demolombe,

  Affiliations INSERM, UMR915, l'Institut du Thorax, Nantes, France, CNRS, ERL3147, Nantes, France, Université de Nantes, Nantes, France

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• Patrick Bruneval,

  Affiliation INSERM, U652, Université Paris V, Paris, France

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• Christopher L. H. Huang,

  Affiliation The Section of Cardiovascular Biology, Departments of Biochemistry and Physiology, University of Cambridge, Cambridge, United Kingdom

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• William H. Colledge,

  Affiliation The Section of Cardiovascular Biology, Departments of Biochemistry and Physiology, University of Cambridge, Cambridge, United Kingdom

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• Andrew A. Grace,

  Affiliation The Section of Cardiovascular Biology, Departments of Biochemistry and Physiology, University of Cambridge, Cambridge, United Kingdom

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• Hervé Le Marec,

  Affiliations INSERM, UMR915, l'Institut du Thorax, Nantes, France, CNRS, ERL3147, Nantes, France, Université de Nantes, Nantes, France, CHU Nantes, l'Institut du Thorax, Nantes, France

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• Arthur A. Wilde,

  Affiliation Department of Cardiology, Academic Medical Center, Amsterdam, The Netherlands

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• Peter J. Mohler,

  Affiliation Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, Iowa, United States of America

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• Denis Escande †,

  † Deceased.

  Affiliations INSERM, UMR915, l'Institut du Thorax, Nantes, France, Université de Nantes, Nantes, France, CHU Nantes, l'Institut du Thorax, Nantes, France

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• Hugues Abriel,

  Affiliation Department of Clinical Research, University of Bern, Bern, Switzerland

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•  [ ... ],
• Flavien Charpentier

  * E-mail: flavien.charpentier@nantes.inserm.fr

  Affiliations INSERM, UMR915, l'Institut du Thorax, Nantes, France, CNRS, ERL3147, Nantes, France, Université de Nantes, Nantes, France, CHU Nantes, l'Institut du Thorax, Nantes, France

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