Structural and Functional Restraints on the Occurrence of Single Amino Acid Variations in Human Proteins

Open Access

Peer-reviewed

Research Article

Sungsam Gong,

Affiliation Biocomputing Group, Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom
⨯
Tom L. Blundell

* E-mail: tom@cryst.bioc.cam.ac.uk

Affiliation Biocomputing Group, Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom
⨯

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Amino acid substitution
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Cancers and neoplasms
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Hydrogen bonding
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Protein structure
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Somatic mutation
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Mutation databases
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Single nucleotide polymorphisms
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Singular value decomposition
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