Unexpected Tolerance of α-Cleavage of the Prion Protein to Sequence Variations

Open Access

Peer-reviewed

Research Article

José B. Oliveira-Martins,

Affiliation Institute of Neuropathology, University Hospital of Zürich, Zurich, Switzerland
⨯
Sei-ichi Yusa,

Affiliation Institute of Neuropathology, University Hospital of Zürich, Zurich, Switzerland
⨯
Anna Maria Calella,

Affiliation Institute of Neuropathology, University Hospital of Zürich, Zurich, Switzerland
⨯
Claire Bridel,

Affiliation Institute of Neuropathology, University Hospital of Zürich, Zurich, Switzerland
⨯
Frank Baumann,

Affiliation Institute of Neuropathology, University Hospital of Zürich, Zurich, Switzerland
⨯
Paolo Dametto,

Affiliation Institute of Neuropathology, University Hospital of Zürich, Zurich, Switzerland
⨯
Adriano Aguzzi

* E-mail: adriano.aguzzi@usz.ch

Affiliation Institute of Neuropathology, University Hospital of Zürich, Zurich, Switzerland
⨯

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Proteolysis
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Transfection
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Mouse models
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Immunoprecipitation
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Toxicity
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Alanine
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Point mutation
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Polymerase chain reaction
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