Active Fragments from Pro- and Antiapoptotic BCL-2 Proteins Have Distinct Membrane Behavior Reflecting Their Functional Divergence

Yannis Guillemin; Jonathan Lopez; Diana Gimenez; Gustavo Fuertes; Juan Garcia Valero; Loïc Blum; Philippe Gonzalo; Jesùs Salgado; Agnès Girard-Egrot; Abdel Aouacheria

doi:10.1371/journal.pone.0009066

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Peer-reviewed

Research Article

Active Fragments from Pro- and Antiapoptotic BCL-2 Proteins Have Distinct Membrane Behavior Reflecting Their Functional Divergence

Yannis Guillemin,

Affiliation Institut de Biologie et Chimie des Protéines (IBCP), CNRS UMR5086, University of Lyon, Lyon, France
⨯
Jonathan Lopez,

Affiliation Institut de Biologie et Chimie des Protéines (IBCP), CNRS UMR5086, University of Lyon, Lyon, France
⨯
Diana Gimenez,

Affiliation Instituto de Ciencia Molecular (ICMol), Universidad de Valencia, Paterna, Valencia, España
⨯
Gustavo Fuertes,

Affiliation Instituto de Ciencia Molecular (ICMol), Universidad de Valencia, Paterna, Valencia, España
⨯
Juan Garcia Valero,

Affiliation Institut de Biologie et Chimie des Protéines (IBCP), CNRS UMR5086, University of Lyon, Lyon, France
⨯
Loïc Blum,

Affiliation Institut de Chimie et Biochimie Moléculaires et Supramoléculaires (ICBMS), CNRS UMR5246, University of Lyon, Villeurbanne, France
⨯
Philippe Gonzalo,

Affiliation Institut de Biologie et Chimie des Protéines (IBCP), CNRS UMR5086, University of Lyon, Lyon, France
⨯
Jesùs Salgado,

Affiliations Instituto de Ciencia Molecular (ICMol), Universidad de Valencia, Paterna, Valencia, España, Departamento de Bioquímica y Biología Molecular, Universidad de Valencia, Burjassot, Valencia, España
⨯
Agnès Girard-Egrot,

Affiliation Institut de Chimie et Biochimie Moléculaires et Supramoléculaires (ICBMS), CNRS UMR5246, University of Lyon, Villeurbanne, France
⨯
Abdel Aouacheria

* E-mail: a.aouacheria@ibcp.fr

Affiliation Institut de Biologie et Chimie des Protéines (IBCP), CNRS UMR5086, University of Lyon, Lyon, France
⨯

Active Fragments from Pro- and Antiapoptotic BCL-2 Proteins Have Distinct Membrane Behavior Reflecting Their Functional Divergence

Yannis Guillemin,
Jonathan Lopez,
Diana Gimenez,
Gustavo Fuertes,
Juan Garcia Valero,
Loïc Blum,
Philippe Gonzalo,
Jesùs Salgado,
Agnès Girard-Egrot,
Abdel Aouacheria

Published: February 5, 2010
https://doi.org/10.1371/journal.pone.0009066

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