ER-α36, a Variant of ER-α, Promotes Tamoxifen Agonist Action in Endometrial Cancer Cells via the MAPK/ERK and PI3K/Akt Pathways

Sheng-Li Lin; Li-Ying Yan; Xin-Tian Zhang; Ju Yuan; Mo Li; Jie Qiao; Zhao-Yi Wang; Qing-Yuan Sun

doi:10.1371/journal.pone.0009013

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Open Access

Peer-reviewed

Research Article

ER-α36, a Variant of ER-α, Promotes Tamoxifen Agonist Action in Endometrial Cancer Cells via the MAPK/ERK and PI3K/Akt Pathways

Sheng-Li Lin,

Affiliation State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences and Graduate School, Chinese Academy of Sciences, Beijing, China
⨯
Li-Ying Yan,

Affiliation Center of Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China
⨯
Xin-Tian Zhang,

Affiliation Department of Medical Microbiology and Immunology, Creighton University Medical School, Omaha, Nebraska, United States of America
⨯
Ju Yuan,

Affiliation State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences and Graduate School, Chinese Academy of Sciences, Beijing, China
⨯
Mo Li,

Affiliation State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences and Graduate School, Chinese Academy of Sciences, Beijing, China
⨯
Jie Qiao ,

* E-mail: jie.qiao@263.net (JQ); zywang@creighton.edu (Z-YW); sunqy@ioz.ac.cn (Q-YS)

Affiliation Center of Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China
⨯
Zhao-Yi Wang ,

* E-mail: jie.qiao@263.net (JQ); zywang@creighton.edu (Z-YW); sunqy@ioz.ac.cn (Q-YS)

Affiliation Department of Medical Microbiology and Immunology, Creighton University Medical School, Omaha, Nebraska, United States of America
⨯
Qing-Yuan Sun

* E-mail: jie.qiao@263.net (JQ); zywang@creighton.edu (Z-YW); sunqy@ioz.ac.cn (Q-YS)

Affiliation State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences and Graduate School, Chinese Academy of Sciences, Beijing, China
⨯

ER-α36, a Variant of ER-α, Promotes Tamoxifen Agonist Action in Endometrial Cancer Cells via the MAPK/ERK and PI3K/Akt Pathways

Sheng-Li Lin,
Li-Ying Yan,
Xin-Tian Zhang,
Ju Yuan,
Mo Li,
Jie Qiao,
Zhao-Yi Wang,
Qing-Yuan Sun

Published: February 2, 2010
https://doi.org/10.1371/journal.pone.0009013

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