Application of Gene Network Analysis Techniques Identifies AXIN1/PDIA2 and Endoglin Haplotypes Associated with Bicuspid Aortic Valve

Open Access

Peer-reviewed

Research Article

Eric C. Wooten,

Affiliation MCRI Center for Translational Genomics, Molecular Cardiology Research Institute, Boston, Massachusetts, United States of America
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Lakshmanan K. Iyer,

Affiliation MCRI Center for Translational Genomics, Molecular Cardiology Research Institute, Boston, Massachusetts, United States of America
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Maria Claudia Montefusco,

Affiliation MCRI Center for Translational Genomics, Molecular Cardiology Research Institute, Boston, Massachusetts, United States of America
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Alyson Kelley Hedgepeth,

Affiliation MCRI Center for Translational Genomics, Molecular Cardiology Research Institute, Boston, Massachusetts, United States of America
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Douglas D. Payne,

Affiliation Cardiothoracic Surgery Division, Tufts Medical Center, Boston, Massachusetts, United States of America
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Navin K. Kapur,

Affiliation MCRI Center for Translational Genomics, Molecular Cardiology Research Institute, Boston, Massachusetts, United States of America
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David E. Housman,

Affiliation Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
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Michael E. Mendelsohn,

Affiliation MCRI Center for Translational Genomics, Molecular Cardiology Research Institute, Boston, Massachusetts, United States of America
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Gordon S. Huggins

* E-mail: ghuggins@tuftsmedicalcenter.org

Affiliation MCRI Center for Translational Genomics, Molecular Cardiology Research Institute, Boston, Massachusetts, United States of America
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Haplotypes
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Single nucleotide polymorphisms
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Genomics
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Aortic valve
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Genetic loci
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Genome analysis
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Aorta
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Genome-wide association studies
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