Two New Pimelic Diphenylamide HDAC Inhibitors Induce Sustained Frataxin Upregulation in Cells from Friedreich's Ataxia Patients and in a Mouse Model

• Myriam Rai,

  Affiliation Laboratoire de Neurologie Expérimentale, Hôpital Erasme, Brussels, Belgium

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• Elisabetta Soragni,

  Affiliation Department of Molecular Biology, The Scripps Research Institute, La Jolla, California, United States of America

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• C. James Chou,

  Current address: Medical University of South Carolina, Charleston, South Carolina, United States of America

  Affiliation Department of Molecular Biology, The Scripps Research Institute, La Jolla, California, United States of America

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• Glenn Barnes,

  Affiliation Repligen Corporation, Waltham, Massachusetts, United States of America

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• Steve Jones,

  Affiliation Repligen Corporation, Waltham, Massachusetts, United States of America

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• James R. Rusche,

  Affiliation Repligen Corporation, Waltham, Massachusetts, United States of America

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• Joel M. Gottesfeld,

  Affiliation Department of Molecular Biology, The Scripps Research Institute, La Jolla, California, United States of America

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• Massimo Pandolfo

  * E-mail: massimo.pandolfo@ulb.ac.be

  Affiliation Laboratoire de Neurologie Expérimentale, Hôpital Erasme, Brussels, Belgium

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