Hedgehog Promotes Neovascularization in Pancreatic Cancers by Regulating Ang-1 and IGF-1 Expression in Bone-Marrow Derived Pro-Angiogenic Cells

• Kazumasa Nakamura ,

  Contributed equally to this work with: Kazumasa Nakamura, Junpei Sasajima

  Affiliation Division of Gastroenterology and Hematology/Oncology, Department of Medicine, Asahikawa Medical College, Asahikawa, Japan

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• Junpei Sasajima ,

  Contributed equally to this work with: Kazumasa Nakamura, Junpei Sasajima

  Affiliation Division of Gastroenterology and Hematology/Oncology, Department of Medicine, Asahikawa Medical College, Asahikawa, Japan

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• Yusuke Mizukami ,

  * E-mail: mizu@asahikawa-med.ac.jp

  Affiliation Division of Gastroenterology and Hematology/Oncology, Department of Medicine, Asahikawa Medical College, Asahikawa, Japan

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• Yoshiaki Sugiyama,

  Affiliation Division of Gastroenterology and Hematology/Oncology, Department of Medicine, Asahikawa Medical College, Asahikawa, Japan

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• Madoka Yamazaki,

  Affiliation Division of Gastroenterology and Hematology/Oncology, Department of Medicine, Asahikawa Medical College, Asahikawa, Japan

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• Rie Fujii,

  Affiliation Division of Gastroenterology and Hematology/Oncology, Department of Medicine, Asahikawa Medical College, Asahikawa, Japan

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• Toru Kawamoto,

  Affiliation Division of Gastroenterology and Hematology/Oncology, Department of Medicine, Asahikawa Medical College, Asahikawa, Japan

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• Kazuya Koizumi,

  Affiliation Division of Gastroenterology and Hematology/Oncology, Department of Medicine, Asahikawa Medical College, Asahikawa, Japan

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• Kazuya Sato,

  Affiliation Division of Gastroenterology and Hematology/Oncology, Department of Medicine, Asahikawa Medical College, Asahikawa, Japan

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• Mikihiro Fujiya,

  Affiliation Division of Gastroenterology and Hematology/Oncology, Department of Medicine, Asahikawa Medical College, Asahikawa, Japan

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• Katsunori Sasaki,

  Affiliation Division of Gastroenterology and Hematology/Oncology, Department of Medicine, Asahikawa Medical College, Asahikawa, Japan

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• Satoshi Tanno,

  Affiliations Division of Gastroenterology and Hematology/Oncology, Department of Medicine, Asahikawa Medical College, Asahikawa, Japan, Department of General Medicine, Asahikawa Medical College, Asahikawa, Japan

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• Toshikatsu Okumura,

  Affiliation Department of General Medicine, Asahikawa Medical College, Asahikawa, Japan

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• Norihiko Shimizu,

  Affiliation Department of Animal Facility, Asahikawa Medical College, Asahikawa, Japan

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• Jun-ichi Kawabe,

  Affiliation Department of Cardiovascular Regeneration and Innovation, Asahikawa Medical College, Asahikawa, Japan

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• Hidenori Karasaki,

  Affiliation Division of Gastroenterological and General Surgery, Department of Surgery, Asahikawa Medical College, Asahikawa, Japan

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• Toru Kono,

  Affiliation Division of Gastroenterological and General Surgery, Department of Surgery, Asahikawa Medical College, Asahikawa, Japan

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• Masaaki Ii,

  Affiliation Group of Vascular Regeneration Research, Institute of Biomedical Research and Innovation, Kobe, Japan

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• Nabeel Bardeesy,

  Affiliation Massachusetts General Hospital Cancer Center and Harvard Medical School, Boston, Massachusetts, United States of America

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• Daniel C. Chung,

  Affiliations Massachusetts General Hospital Cancer Center and Harvard Medical School, Boston, Massachusetts, United States of America, Gastrointestinal Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States of America

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•  [ ... ],
• Yutaka Kohgo

  Affiliation Division of Gastroenterology and Hematology/Oncology, Department of Medicine, Asahikawa Medical College, Asahikawa, Japan

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