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Open Access

Peer-reviewed

Research Article

Dendritic Cell Mediated Delivery of Plasmid DNA Encoding LAMP/HIV-1 Gag Fusion Immunogen Enhances T Cell Epitope Responses in HLA DR4 Transgenic Mice

Gregory G. Simon ,

* E-mail: gsimon2@jhmi.edu

Affiliation Department of Pharmacology and Molecular Sciences, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
⨯
Yongli Hu,

Affiliation Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
⨯
Asif M. Khan,

Affiliation Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
⨯
Jingshi Zhou,

Affiliation Department of Pharmacology and Molecular Sciences, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
⨯
Jerome Salmon,

Affiliation Department of Pharmacology and Molecular Sciences, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
⨯
Priya R. Chikhlikar,

Affiliation Department of Pharmacology and Molecular Sciences, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
⨯
Keun-Ok Jung,

Affiliation Department of Pharmacology and Molecular Sciences, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
⨯
Ernesto T. A. Marques,

Affiliations Department of Pharmacology and Molecular Sciences, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Department of Medicine, Division of Infectious Diseases, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
⨯
J. Thomas August

Affiliations Department of Pharmacology and Molecular Sciences, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Department of Medicine, Division of Infectious Diseases, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
⨯

Dendritic Cell Mediated Delivery of Plasmid DNA Encoding LAMP/HIV-1 Gag Fusion Immunogen Enhances T Cell Epitope Responses in HLA DR4 Transgenic Mice

Gregory G. Simon,
Yongli Hu,
Asif M. Khan,
Jingshi Zhou,
Jerome Salmon,
Priya R. Chikhlikar,
Keun-Ok Jung,
Ernesto T. A. Marques,
J. Thomas August

x

Published: January 5, 2010
https://doi.org/10.1371/journal.pone.0008574

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T cells
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Enzyme-linked immunoassays
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HIV-1
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Immune response
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Transfection
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Mouse models
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HIV vaccines
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HIV
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