Echinocandin Treatment of Pneumocystis Pneumonia in Rodent Models Depletes Cysts Leaving Trophic Burdens That Cannot Transmit the Infection

Melanie T. Cushion; Michael J. Linke; Alan Ashbaugh; Tom Sesterhenn; Margaret S. Collins; Keeley Lynch; Ronald Brubaker; Peter D. Walzer

doi:10.1371/journal.pone.0008524

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Peer-reviewed

Research Article

Echinocandin Treatment of Pneumocystis Pneumonia in Rodent Models Depletes Cysts Leaving Trophic Burdens That Cannot Transmit the Infection

Melanie T. Cushion ,

* E-mail: melanie.cushion@uc.edu

Affiliations College of Medicine, University of Cincinnati, Cincinnati, Ohio, United States of America, Veterans Administration Medical Center, Cincinnati, Ohio, United States of America
⨯
Michael J. Linke,

Affiliation Veterans Administration Medical Center, Cincinnati, Ohio, United States of America
⨯
Alan Ashbaugh,

Affiliations College of Medicine, University of Cincinnati, Cincinnati, Ohio, United States of America, Veterans Administration Medical Center, Cincinnati, Ohio, United States of America
⨯
Tom Sesterhenn,

Affiliations College of Medicine, University of Cincinnati, Cincinnati, Ohio, United States of America, Veterans Administration Medical Center, Cincinnati, Ohio, United States of America
⨯
Margaret S. Collins,

Affiliations College of Medicine, University of Cincinnati, Cincinnati, Ohio, United States of America, Veterans Administration Medical Center, Cincinnati, Ohio, United States of America
⨯
Keeley Lynch,

Affiliations College of Medicine, University of Cincinnati, Cincinnati, Ohio, United States of America, Veterans Administration Medical Center, Cincinnati, Ohio, United States of America
⨯
Ronald Brubaker,

Affiliation Department of Pathology, The Christ Hospital, Cincinnati, Ohio, United States of America
⨯
Peter D. Walzer

Affiliations College of Medicine, University of Cincinnati, Cincinnati, Ohio, United States of America, Veterans Administration Medical Center, Cincinnati, Ohio, United States of America
⨯

Echinocandin Treatment of Pneumocystis Pneumonia in Rodent Models Depletes Cysts Leaving Trophic Burdens That Cannot Transmit the Infection

Melanie T. Cushion,
Michael J. Linke,
Alan Ashbaugh,
Tom Sesterhenn,
Margaret S. Collins,
Keeley Lynch,
Ronald Brubaker,
Peter D. Walzer

Published: January 29, 2010
https://doi.org/10.1371/journal.pone.0008524

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Prophylaxis
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