Cellular Levels of HIV Unspliced RNA from Patients on Combination Antiretroviral Therapy with Undetectable Plasma Viremia Predict the Therapy Outcome

Open Access

Peer-reviewed

Research Article

Alexander O. Pasternak,

Affiliation Department of Medical Microbiology, Laboratory of Experimental Virology, Center for Infection and Immunity Amsterdam (CINIMA), Academic Medical Center of the University of Amsterdam, Amsterdam, The Netherlands
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Suzanne Jurriaans,

Affiliation Department of Medical Microbiology, Laboratory of Clinical Virology, Academic Medical Center of the University of Amsterdam, Amsterdam, The Netherlands
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Margreet Bakker,

Affiliation Department of Medical Microbiology, Laboratory of Experimental Virology, Center for Infection and Immunity Amsterdam (CINIMA), Academic Medical Center of the University of Amsterdam, Amsterdam, The Netherlands
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Jan M. Prins,

Affiliation Department of Internal Medicine, Division of Infectious Diseases, Tropical Medicine and AIDS, Academic Medical Center of the University of Amsterdam, Amsterdam, The Netherlands
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Ben Berkhout,

Affiliation Department of Medical Microbiology, Laboratory of Experimental Virology, Center for Infection and Immunity Amsterdam (CINIMA), Academic Medical Center of the University of Amsterdam, Amsterdam, The Netherlands
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Vladimir V. Lukashov

* E-mail: v.lukashov@amc.uva.nl

Affiliation Department of Medical Microbiology, Laboratory of Experimental Virology, Center for Infection and Immunity Amsterdam (CINIMA), Academic Medical Center of the University of Amsterdam, Amsterdam, The Netherlands
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HIV-1
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Viremia
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Polymerase chain reaction
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Antiretroviral therapy
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Blood plasma
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Protease inhibitor therapy
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Medical risk factors
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Viral replication
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