Polymerase-Endonuclease Amplification Reaction (PEAR) for Large-Scale Enzymatic Production of Antisense Oligonucleotides

Open Access

Peer-reviewed

Research Article

Xiaolong Wang ,

* E-mail: xiaolong@ouc.edu.cn

Affiliation Department of Biotechnology, Ocean University of China, Qingdao, Shandong, People's Republic of China
⨯
Deming Gou,

Affiliation Department of Pediatrics, University of Illinois at Chicago, Chicago, Illinois, United States of America
⨯
Shuang-yong Xu

Affiliation New England Biolabs Inc., Ipswich, Massachusetts, United States of America
⨯

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Oligonucleotides
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Antisense oligonucleotides
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DNA polymerase
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MicroRNAs
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Tandem repeats
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Polymerase chain reaction
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Capillary electrophoresis
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Oligonucleotide synthesis
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