Bone Marrow Osteoblastic Niche: A New Model to Study Physiological Regulation of Megakaryopoiesis

Open Access

Peer-reviewed

Research Article

Isabella Pallotta,

Affiliations Department of Biomedical Engineering, Tufts University, Medford, Massachusetts, United States of America, Department of Biochemistry, University of Pavia, Pavia, Italy
⨯
Michael Lovett,

Affiliation Department of Biomedical Engineering, Tufts University, Medford, Massachusetts, United States of America
⨯
William Rice,

Affiliation Department of Biomedical Engineering, Tufts University, Medford, Massachusetts, United States of America
⨯
David L. Kaplan ,

* E-mail: david.kaplan@tufts.edu (DLK); alessandra.balduini@tufts.edu (AB)

Affiliation Department of Biomedical Engineering, Tufts University, Medford, Massachusetts, United States of America
⨯
Alessandra Balduini

* E-mail: david.kaplan@tufts.edu (DLK); alessandra.balduini@tufts.edu (AB)

Affiliations Department of Biomedical Engineering, Tufts University, Medford, Massachusetts, United States of America, Department of Biochemistry, University of Pavia, Pavia, Italy
⨯

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Collagens
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Osteoblast differentiation
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Stem cell niche
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Oxygen
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Platelets
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Integrins
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Hypoxia
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Megakaryocytes
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