Secreted Gaussia Luciferase as a Biomarker for Monitoring Tumor Progression and Treatment Response of Systemic Metastases

Euiheon Chung; Hiroshi Yamashita; Patrick Au; Bakhos A. Tannous; Dai Fukumura; Rakesh K. Jain

doi:10.1371/journal.pone.0008316

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Peer-reviewed

Research Article

Secreted Gaussia Luciferase as a Biomarker for Monitoring Tumor Progression and Treatment Response of Systemic Metastases

Euiheon Chung ,

Contributed equally to this work with: Euiheon Chung, Hiroshi Yamashita

Affiliation Edwin L. Steele Laboratory, Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Hiroshi Yamashita ,

Contributed equally to this work with: Euiheon Chung, Hiroshi Yamashita

Affiliation Edwin L. Steele Laboratory, Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Patrick Au,

Affiliation Edwin L. Steele Laboratory, Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Bakhos A. Tannous ,

* E-mail: btannous@hms.harvard.edu (BAT); dai@steele.mgh.harvard.edu (DF); jain@steele.mgh.harvard.edu (RKJ)

Affiliations Molecular Neurogenetics Unit, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Radiology, Center for Molecular Imaging Research, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Dai Fukumura ,

* E-mail: btannous@hms.harvard.edu (BAT); dai@steele.mgh.harvard.edu (DF); jain@steele.mgh.harvard.edu (RKJ)

Affiliation Edwin L. Steele Laboratory, Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Rakesh K. Jain

* E-mail: btannous@hms.harvard.edu (BAT); dai@steele.mgh.harvard.edu (DF); jain@steele.mgh.harvard.edu (RKJ)

Affiliation Edwin L. Steele Laboratory, Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
⨯

Secreted Gaussia Luciferase as a Biomarker for Monitoring Tumor Progression and Treatment Response of Systemic Metastases

Euiheon Chung,
Hiroshi Yamashita,
Patrick Au,
Bakhos A. Tannous,
Dai Fukumura,
Rakesh K. Jain

Published: December 15, 2009
https://doi.org/10.1371/journal.pone.0008316

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