Hepatitis C Virus (HCV) Infection May Elicit Neutralizing Antibodies Targeting Epitopes Conserved in All Viral Genotypes

Nicasio Mancini; Roberta A. Diotti; Mario Perotti; Giuseppe Sautto; Nicola Clementi; Giovanni Nitti; Arvind H. Patel; Jonathan K. Ball; Massimo Clementi; Roberto Burioni

doi:10.1371/journal.pone.0008254

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Open Access

Peer-reviewed

Research Article

Hepatitis C Virus (HCV) Infection May Elicit Neutralizing Antibodies Targeting Epitopes Conserved in All Viral Genotypes

Nicasio Mancini ,

Contributed equally to this work with: Nicasio Mancini, Roberta A. Diotti

* E-mail: mancini.nicasio@hsr.it

Affiliation Laboratorio di Microbiologia e Virologia, Università “Vita-Salute” San Raffaele, Milano, Italia
⨯
Roberta A. Diotti ,

Contributed equally to this work with: Nicasio Mancini, Roberta A. Diotti

Affiliation Laboratorio di Microbiologia e Virologia, Università “Vita-Salute” San Raffaele, Milano, Italia
⨯
Mario Perotti,

Affiliation Laboratorio di Microbiologia e Virologia, Università “Vita-Salute” San Raffaele, Milano, Italia
⨯
Giuseppe Sautto,

Affiliation Laboratorio di Microbiologia e Virologia, Università “Vita-Salute” San Raffaele, Milano, Italia
⨯
Nicola Clementi,

Affiliation Laboratorio di Microbiologia e Virologia, Università “Vita-Salute” San Raffaele, Milano, Italia
⨯
Giovanni Nitti,

Affiliation Laboratorio di Microbiologia e Virologia, Università “Vita-Salute” San Raffaele, Milano, Italia
⨯
Arvind H. Patel,

Affiliation MRC Virology Unit, Institute of Virology, University of Glasgow, Church Street, Glasgow, United Kingdom
⨯
Jonathan K. Ball,

Affiliation Institute of Infection, Immunity and Inflammation, School of Molecular Medical Sciences, University of Nottingham, Queen's Medical Centre, Nottingham, United Kingdom
⨯
Massimo Clementi,

Affiliation Laboratorio di Microbiologia e Virologia, Università “Vita-Salute” San Raffaele, Milano, Italia
⨯
Roberto Burioni

Affiliation Laboratorio di Microbiologia e Virologia, Università “Vita-Salute” San Raffaele, Milano, Italia
⨯

Hepatitis C Virus (HCV) Infection May Elicit Neutralizing Antibodies Targeting Epitopes Conserved in All Viral Genotypes

Nicasio Mancini,
Roberta A. Diotti,
Mario Perotti,
Giuseppe Sautto,
Nicola Clementi,
Giovanni Nitti,
Arvind H. Patel,
Jonathan K. Ball,
Massimo Clementi,
Roberto Burioni

Published: December 11, 2009
https://doi.org/10.1371/journal.pone.0008254

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Hepatitis C virus
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Antibodies
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Enzyme-linked immunoassays
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Epitope mapping
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Glycoproteins
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Peptide mapping
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Transfection
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Viral persistence and latency
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