P-Glycoprotein Acts as an Immunomodulator during Neuroinflammation

Gijs Kooij; Ronald Backer; Jasper J. Koning; Arie Reijerkerk; Jack van Horssen; Susanne M. A. van der Pol; Joost Drexhage; Alfred Schinkel; Christine D. Dijkstra; Joke M. M. den Haan; Teunis B. H. Geijtenbeek; Helga E. de Vries

doi:10.1371/journal.pone.0008212

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Open Access

Peer-reviewed

Research Article

P-Glycoprotein Acts as an Immunomodulator during Neuroinflammation

Gijs Kooij,

Affiliation Department of Molecular Cell Biology and Immunology, VU University Medical Center, Amsterdam, The Netherlands
⨯
Ronald Backer ,

Contributed equally to this work with: Ronald Backer, Jasper J. Koning

Affiliation Department of Molecular Cell Biology and Immunology, VU University Medical Center, Amsterdam, The Netherlands
⨯
Jasper J. Koning ,

Contributed equally to this work with: Ronald Backer, Jasper J. Koning

Affiliation Department of Molecular Cell Biology and Immunology, VU University Medical Center, Amsterdam, The Netherlands
⨯
Arie Reijerkerk,

Affiliation Department of Molecular Cell Biology and Immunology, VU University Medical Center, Amsterdam, The Netherlands
⨯
Jack van Horssen,

Affiliation Department of Molecular Cell Biology and Immunology, VU University Medical Center, Amsterdam, The Netherlands
⨯
Susanne M. A. van der Pol,

Affiliation Department of Molecular Cell Biology and Immunology, VU University Medical Center, Amsterdam, The Netherlands
⨯
Joost Drexhage,

Affiliation Department of Molecular Cell Biology and Immunology, VU University Medical Center, Amsterdam, The Netherlands
⨯
Alfred Schinkel,

Affiliation Department of Molecular Biology, Netherlands Cancer Institute (NKI), Amsterdam, The Netherlands
⨯
Christine D. Dijkstra,

Affiliation Department of Molecular Cell Biology and Immunology, VU University Medical Center, Amsterdam, The Netherlands
⨯
Joke M. M. den Haan,

Affiliation Department of Molecular Cell Biology and Immunology, VU University Medical Center, Amsterdam, The Netherlands
⨯
Teunis B. H. Geijtenbeek,

Affiliation Center for Experimental and Molecular Medicine, Academic Medical Center, Amsterdam, The Netherlands
⨯
Helga E. de Vries

* E-mail: He.devries@vumc.nl

Affiliation Department of Molecular Cell Biology and Immunology, VU University Medical Center, Amsterdam, The Netherlands
⨯

P-Glycoprotein Acts as an Immunomodulator during Neuroinflammation

Gijs Kooij,
Ronald Backer,
Jasper J. Koning,
Arie Reijerkerk,
Jack van Horssen,
Susanne M. A. van der Pol,
Joost Drexhage,
Alfred Schinkel,
Christine D. Dijkstra,
Joke M. M. den Haan

Published: December 8, 2009
https://doi.org/10.1371/journal.pone.0008212

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