Integrative Discovery of Epigenetically Derepressed Cancer Testis Antigens in NSCLC

Chad A. Glazer; Ian M. Smith; Michael F. Ochs; Shahnaz Begum; William Westra; Steven S. Chang; Wenyue Sun; Sheetal Bhan; Zubair Khan; Steven Ahrendt; Joseph A. Califano

doi:10.1371/journal.pone.0008189

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Open Access

Peer-reviewed

Research Article

Integrative Discovery of Epigenetically Derepressed Cancer Testis Antigens in NSCLC

Chad A. Glazer,

Affiliation Department of Otolaryngology—Head and Neck Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America
⨯
Ian M. Smith,

Affiliation Department of Otolaryngology—Head and Neck Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America
⨯
Michael F. Ochs,

Affiliation Division of Oncology Biostatistics, Department of Oncology, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America
⨯
Shahnaz Begum,

Affiliation Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America
⨯
William Westra,

Affiliation Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America
⨯
Steven S. Chang,

Affiliation Department of Otolaryngology—Head and Neck Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America
⨯
Wenyue Sun,

Affiliation Department of Otolaryngology—Head and Neck Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America
⨯
Sheetal Bhan,

Affiliation Department of Otolaryngology—Head and Neck Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America
⨯
Zubair Khan,

Affiliation Department of Otolaryngology—Head and Neck Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America
⨯
Steven Ahrendt,

Affiliation Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States of America
⨯
Joseph A. Califano

* E-mail: jcalifa@jhmi.edu

Affiliations Department of Otolaryngology—Head and Neck Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America, Milton J Dance Head and Neck Center, Greater Baltimore Medical Center, Baltimore, Maryland, United States of America
⨯

Integrative Discovery of Epigenetically Derepressed Cancer Testis Antigens in NSCLC

Chad A. Glazer,
Ian M. Smith,
Michael F. Ochs,
Shahnaz Begum,
William Westra,
Steven S. Chang,
Wenyue Sun,
Sheetal Bhan,
Zubair Khan,
Steven Ahrendt

Published: December 4, 2009
https://doi.org/10.1371/journal.pone.0008189

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DNA methylation
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