Original Encounter with Antigen Determines Antigen-Presenting Cell Imprinting of the Quality of the Immune Response in Mice

Valérie Abadie; Olivia Bonduelle; Darragh Duffy; Christophe Parizot; Bernard Verrier; Béhazine Combadière

doi:10.1371/journal.pone.0008159

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Research Article

Original Encounter with Antigen Determines Antigen-Presenting Cell Imprinting of the Quality of the Immune Response in Mice

Valérie Abadie,

Current address: Department of Medicine, University of Chicago, Chicago, Illinois, United States of America

Affiliations Institut National de la Santé et de la Recherche Médicale (INSERM) U945, Paris, France, University of Pierre and Marie Curie (UPMC)- Univ Paris 06, Paris, France, Assistance-Publique/Hopitaux-de-Paris, Immunity and Infection, Paris, France
⨯
Olivia Bonduelle,

Affiliations Institut National de la Santé et de la Recherche Médicale (INSERM) U945, Paris, France, University of Pierre and Marie Curie (UPMC)- Univ Paris 06, Paris, France, Assistance-Publique/Hopitaux-de-Paris, Immunity and Infection, Paris, France
⨯
Darragh Duffy,

Affiliations Institut National de la Santé et de la Recherche Médicale (INSERM) U945, Paris, France, University of Pierre and Marie Curie (UPMC)- Univ Paris 06, Paris, France, Assistance-Publique/Hopitaux-de-Paris, Immunity and Infection, Paris, France
⨯
Christophe Parizot,

Affiliations Institut National de la Santé et de la Recherche Médicale (INSERM) U945, Paris, France, University of Pierre and Marie Curie (UPMC)- Univ Paris 06, Paris, France, Assistance-Publique/Hopitaux-de-Paris, Immunity and Infection, Paris, France
⨯
Bernard Verrier,

Affiliation Institut de Biologie et Chimie des Protéines, UMR 5086 CNRS/UCBL, Lyon, France
⨯
Béhazine Combadière

* E-mail: behazine.combadiere@upmc.fr

Affiliations Institut National de la Santé et de la Recherche Médicale (INSERM) U945, Paris, France, University of Pierre and Marie Curie (UPMC)- Univ Paris 06, Paris, France, Assistance-Publique/Hopitaux-de-Paris, Immunity and Infection, Paris, France
⨯

Original Encounter with Antigen Determines Antigen-Presenting Cell Imprinting of the Quality of the Immune Response in Mice

Valérie Abadie,
Olivia Bonduelle,
Darragh Duffy,
Christophe Parizot,
Bernard Verrier,
Béhazine Combadière

Published: December 7, 2009
https://doi.org/10.1371/journal.pone.0008159

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T cells
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Antigen-presenting cells
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Cytotoxic T cells
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Immune response
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Cytokines
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Antigen presentation
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Inoculation
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