Role of Toll-Like Receptors 2 and 4 in Pulmonary Inflammation and Injury Induced by Pneumolysin in Mice

Open Access

Peer-reviewed

Research Article

Mark C. Dessing ,

* E-mail: m.c.dessing@amc.uva.nl

Affiliations Center for Infection and Immunity Amsterdam (CINIMA), Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands, Center for Experimental and Molecular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
⨯
Robert A. Hirst,

Affiliation Department of Infection, Inflammation and Immunity, University of Leicester, Leicester, United Kingdom
⨯
Alex F. de Vos,

Affiliations Center for Infection and Immunity Amsterdam (CINIMA), Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands, Center for Experimental and Molecular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
⨯
Tom van der Poll

Affiliations Center for Infection and Immunity Amsterdam (CINIMA), Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands, Center for Experimental and Molecular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
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Inflammation
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Toll-like receptors
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Neutrophils
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Cytokines
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Alveolar macrophages
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HEK 293 cells
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Pneumococcus
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Bacterial pathogens
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