PGC-1-Related Coactivator Modulates Mitochondrial-Nuclear Crosstalk through Endogenous Nitric Oxide in a Cellular Model of Oncocytic Thyroid Tumours

Mahatsangy Raharijaona; Soazig Le Pennec; Julie Poirier; Delphine Mirebeau-Prunier; Clothilde Rouxel; Caroline Jacques; Jean-Fred Fontaine; Yves Malthiery; Rémi Houlgatte; Frédérique Savagner

doi:10.1371/journal.pone.0007964

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Research Article

PGC-1-Related Coactivator Modulates Mitochondrial-Nuclear Crosstalk through Endogenous Nitric Oxide in a Cellular Model of Oncocytic Thyroid Tumours

Mahatsangy Raharijaona ,

Contributed equally to this work with: Mahatsangy Raharijaona, Soazig Le Pennec

Affiliations INSERM, UMR 915, l'institut du Thorax, Nantes, France, Université de Nantes, Nantes, France
⨯
Soazig Le Pennec ,

Contributed equally to this work with: Mahatsangy Raharijaona, Soazig Le Pennec

Affiliations INSERM, UMR 694, Angers, France, Université d'Angers, Angers, France
⨯
Julie Poirier,

Affiliations INSERM, UMR 694, Angers, France, Université d'Angers, Angers, France
⨯
Delphine Mirebeau-Prunier,

Affiliations INSERM, UMR 694, Angers, France, Université d'Angers, Angers, France, CHU Angers, Laboratoire de Biochimie, Angers, France
⨯
Clothilde Rouxel,

Affiliations INSERM, UMR 694, Angers, France, Université d'Angers, Angers, France
⨯
Caroline Jacques,

Affiliations INSERM, UMR 694, Angers, France, Université d'Angers, Angers, France
⨯
Jean-Fred Fontaine,

Affiliations INSERM, UMR 694, Angers, France, Université d'Angers, Angers, France
⨯
Yves Malthiery,

Affiliations INSERM, UMR 694, Angers, France, Université d'Angers, Angers, France, CHU Angers, Laboratoire de Biochimie, Angers, France
⨯
Rémi Houlgatte,

Affiliations INSERM, UMR 915, l'institut du Thorax, Nantes, France, Université de Nantes, Nantes, France
⨯
Frédérique Savagner

* E-mail: frederique.savagner@univ-angers.fr.

Affiliations INSERM, UMR 915, l'institut du Thorax, Nantes, France, INSERM, UMR 694, Angers, France, Université d'Angers, Angers, France, CHU Angers, Laboratoire de Biochimie, Angers, France
⨯

PGC-1-Related Coactivator Modulates Mitochondrial-Nuclear Crosstalk through Endogenous Nitric Oxide in a Cellular Model of Oncocytic Thyroid Tumours

Mahatsangy Raharijaona,
Soazig Le Pennec,
Julie Poirier,
Delphine Mirebeau-Prunier,
Clothilde Rouxel,
Caroline Jacques,
Jean-Fred Fontaine,
Yves Malthiery,
Rémi Houlgatte,
Frédérique Savagner

Published: November 23, 2009
https://doi.org/10.1371/journal.pone.0007964

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Small interfering RNA
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Gene expression
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