Early Life Exposure to Famine and Colorectal Cancer Risk: A Role for Epigenetic Mechanisms

Laura A. E. Hughes; Piet A. van den Brandt; Adriaan P. de Bruïne; Kim A. D. Wouters; Sarah Hulsmans; Angela Spiertz; R. Alexandra Goldbohm; Anton F. P. M. de Goeij; James G. Herman; Matty P. Weijenberg; Manon van Engeland

doi:10.1371/journal.pone.0007951

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Open Access

Peer-reviewed

Research Article

Early Life Exposure to Famine and Colorectal Cancer Risk: A Role for Epigenetic Mechanisms

Laura A. E. Hughes,

Affiliation Department of Epidemiology, GROW School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, The Netherlands
⨯
Piet A. van den Brandt,

Affiliation Department of Epidemiology, GROW School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, The Netherlands
⨯
Adriaan P. de Bruïne,

Affiliation Department of Pathology, GROW School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, The Netherlands
⨯
Kim A. D. Wouters,

Affiliation Department of Pathology, GROW School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, The Netherlands
⨯
Sarah Hulsmans,

Affiliation Department of Pathology, GROW School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, The Netherlands
⨯
Angela Spiertz,

Affiliation Department of Prevention and Health, TNO Quality of Life, Leiden, The Netherlands
⨯
R. Alexandra Goldbohm,

Affiliation Department of Prevention and Health, TNO Quality of Life, Leiden, The Netherlands
⨯
Anton F. P. M. de Goeij,

Affiliation Department of Pathology, GROW School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, The Netherlands
⨯
James G. Herman,

Affiliation Sidney Kimmel Comprehensive Cancer Center, John Hopkins University School of Medicine, Baltimore, Maryland, United States of America
⨯
Matty P. Weijenberg,

Affiliation Department of Epidemiology, GROW School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, The Netherlands
⨯
Manon van Engeland

* E-mail: manon.van.engeland@mumc.nl

Affiliation Department of Pathology, GROW School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, The Netherlands
⨯

Early Life Exposure to Famine and Colorectal Cancer Risk: A Role for Epigenetic Mechanisms

Laura A. E. Hughes,
Piet A. van den Brandt,
Adriaan P. de Bruïne,
Kim A. D. Wouters,
Sarah Hulsmans,
Angela Spiertz,
R. Alexandra Goldbohm,
Anton F. P. M. de Goeij,
James G. Herman,
Matty P. Weijenberg

Published: November 23, 2009
https://doi.org/10.1371/journal.pone.0007951

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