Dihydroartemisinin-Piperaquine and Artemether-Lumefantrine for Treating Uncomplicated Malaria in African Children: A Randomised, Non-Inferiority Trial

Quique Bassat; Modest Mulenga; Halidou Tinto; Patrice Piola; Steffen Borrmann; Clara Menéndez; Michael Nambozi; Innocent Valéa; Carolyn Nabasumba; Philip Sasi; Antonella Bacchieri; Marco Corsi; David Ubben; Ambrose Talisuna; Umberto D'Alessandro

doi:10.1371/journal.pone.0007871

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Open Access

Peer-reviewed

Research Article

Dihydroartemisinin-Piperaquine and Artemether-Lumefantrine for Treating Uncomplicated Malaria in African Children: A Randomised, Non-Inferiority Trial

Quique Bassat,

Affiliations Barcelona Centre for International Health Research (CRESIB), Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Universitat de Barcelona, Barcelona, Spain, Manhiça Health Research Centre (CISM), Manhiça, Mozambique
⨯
Modest Mulenga,

Affiliation Tropical Disease Research Centre, Ndola, Zambia
⨯
Halidou Tinto,

Affiliation Centre Muraz, Bobo-Dioulasso, Burkina Faso, IRSS/DRO, Bobo-Dioulasso, Burkina Faso
⨯
Patrice Piola,

Affiliation Epicentre/MSF, Mbarara, Uganda
⨯
Steffen Borrmann,

Affiliations Kenya Medical Research Institute, Kilifi, Kenya, University of Heidelberg, Heidelberg, Germany
⨯
Clara Menéndez,

Affiliations Barcelona Centre for International Health Research (CRESIB), Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Universitat de Barcelona, Barcelona, Spain, Manhiça Health Research Centre (CISM), Manhiça, Mozambique
⨯
Michael Nambozi,

Affiliation Tropical Disease Research Centre, Ndola, Zambia
⨯
Innocent Valéa,

Affiliation Centre Muraz, Bobo-Dioulasso, Burkina Faso, IRSS/DRO, Bobo-Dioulasso, Burkina Faso
⨯
Carolyn Nabasumba,

Affiliation Epicentre/MSF, Mbarara, Uganda
⨯
Philip Sasi,

Affiliations Kenya Medical Research Institute, Kilifi, Kenya, Department of Clinical Pharmacology, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania
⨯
Antonella Bacchieri,

Affiliation Sigma Tau Industrie Farmaceutiche Riunite, Pomezia, Rome, Italy
⨯
Marco Corsi,

Affiliation Sigma Tau Industrie Farmaceutiche Riunite, Pomezia, Rome, Italy
⨯
David Ubben,

Affiliation Medicines for Malaria Venture, Geneva, Switzerland
⨯
Ambrose Talisuna,

Affiliation Prince Leopold Institute of Tropical Medicine, Antwerp, Belgium
⨯
Umberto D'Alessandro

* E-mail: udalessandro@itg.be

Affiliation Prince Leopold Institute of Tropical Medicine, Antwerp, Belgium
⨯

Dihydroartemisinin-Piperaquine and Artemether-Lumefantrine for Treating Uncomplicated Malaria in African Children: A Randomised, Non-Inferiority Trial

Quique Bassat,
Modest Mulenga,
Halidou Tinto,
Patrice Piola,
Steffen Borrmann,
Clara Menéndez,
Michael Nambozi,
Innocent Valéa,
Carolyn Nabasumba,
Philip Sasi

Published: November 17, 2009
https://doi.org/10.1371/journal.pone.0007871

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