Cleavage of the SARS Coronavirus Spike Glycoprotein by Airway Proteases Enhances Virus Entry into Human Bronchial Epithelial Cells In Vitro

• Yiu-Wing Kam,

  Affiliations HKU-Pasteur Research Center, The University of Hong Kong, Hong Kong SAR, China, Singapore Immunology Network, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore

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• Yuushi Okumura,

  Affiliations Department of Nutritional Physiology, Institute of Health Biosciences, University of Tokushima Graduate School, Tokushima, Japan, Division of Enzyme Chemistry, Institute for Enzyme Research, University of Tokushima Graduate School, Tokushima, Japan

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• Hiroshi Kido,

  Affiliation Division of Enzyme Chemistry, Institute for Enzyme Research, University of Tokushima Graduate School, Tokushima, Japan

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• Lisa F. P. Ng,

  Affiliations Singapore Immunology Network, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore, Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore

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• Roberto Bruzzone ,

  * E-mail: bruzzone@hku.hk

  Affiliation HKU-Pasteur Research Center, The University of Hong Kong, Hong Kong SAR, China

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• Ralf Altmeyer

  Affiliation HKU-Pasteur Research Center, The University of Hong Kong, Hong Kong SAR, China

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