Immunopurification of Pathological Prion Protein Aggregates

Open Access

Peer-reviewed

Research Article

Emiliano Biasini,

Affiliations Dulbecco Telethon Institute, Milan, Italy, Department of Neuroscience, Mario Negri Institute for Pharmacological Research, Milan, Italy, Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, Missouri, United States of America
⨯
Laura Tapella,

Affiliations Dulbecco Telethon Institute, Milan, Italy, Department of Neuroscience, Mario Negri Institute for Pharmacological Research, Milan, Italy
⨯
Susanna Mantovani,

Affiliations Dulbecco Telethon Institute, Milan, Italy, Department of Neuroscience, Mario Negri Institute for Pharmacological Research, Milan, Italy
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Matteo Stravalaci,

Affiliation Department of Biochemistry and Molecular Pharmacology, Mario Negri Institute for Pharmacological Research, Milan, Italy
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Marco Gobbi,

Affiliation Department of Biochemistry and Molecular Pharmacology, Mario Negri Institute for Pharmacological Research, Milan, Italy
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David A. Harris,

Current address: Department of Biochemistry, Boston University School of Medicine, Boston, Massachusetts, United States of America

Affiliation Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, Missouri, United States of America
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Roberto Chiesa

* E-mail: roberto.chiesa@marionegri.it

Affiliations Dulbecco Telethon Institute, Milan, Italy, Department of Neuroscience, Mario Negri Institute for Pharmacological Research, Milan, Italy
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Immunoprecipitation
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Prion diseases
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Mouse models
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Centrifugation
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Proteases
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Sonication
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Monoclonal antibodies
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Neurons
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