Versatile Assays for High Throughput Screening for Activators or Inhibitors of Intracellular Proteases and Their Cellular Regulators

Hideki Hayashi; Michael Cuddy; Vincent Chih-Wen Shu; Kenneth W. Yip; Charitha Madiraju; Paul Diaz; Toshifumi Matsuyama; Muneshige Kaibara; Kohtaro Taniyama; Stefan Vasile; Eduard Sergienko; John C. Reed

doi:10.1371/journal.pone.0007655

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Open Access

Peer-reviewed

Research Article

Versatile Assays for High Throughput Screening for Activators or Inhibitors of Intracellular Proteases and Their Cellular Regulators

Hideki Hayashi,

Affiliations Burnham Institute for Medical Research, La Jolla, California, United States of America, Nagasaki University Graduate School of Biomedical Sciences, Sakamoto, Nagasaki, Japan
⨯
Michael Cuddy,

Affiliation Burnham Institute for Medical Research, La Jolla, California, United States of America
⨯
Vincent Chih-Wen Shu,

Affiliation Burnham Institute for Medical Research, La Jolla, California, United States of America
⨯
Kenneth W. Yip,

Affiliation Burnham Institute for Medical Research, La Jolla, California, United States of America
⨯
Charitha Madiraju,

Affiliation Burnham Institute for Medical Research, La Jolla, California, United States of America
⨯
Paul Diaz,

Affiliation Burnham Institute for Medical Research, La Jolla, California, United States of America
⨯
Toshifumi Matsuyama,

Affiliation Nagasaki University Graduate School of Biomedical Sciences, Sakamoto, Nagasaki, Japan
⨯
Muneshige Kaibara,

Affiliation Nagasaki University Graduate School of Biomedical Sciences, Sakamoto, Nagasaki, Japan
⨯
Kohtaro Taniyama,

Affiliation Nagasaki University Graduate School of Biomedical Sciences, Sakamoto, Nagasaki, Japan
⨯
Stefan Vasile,

Affiliations Burnham Institute for Medical Research, La Jolla, California, United States of America, Conrad Prebys Center for Chemical Genomics, Burnham Institute for Medical Research, La Jolla, California, United States of America
⨯
Eduard Sergienko,

Affiliations Burnham Institute for Medical Research, La Jolla, California, United States of America, Conrad Prebys Center for Chemical Genomics, Burnham Institute for Medical Research, La Jolla, California, United States of America
⨯
John C. Reed

* E-mail: Reedoffice@burnham.org

Affiliations Burnham Institute for Medical Research, La Jolla, California, United States of America, Conrad Prebys Center for Chemical Genomics, Burnham Institute for Medical Research, La Jolla, California, United States of America
⨯

Versatile Assays for High Throughput Screening for Activators or Inhibitors of Intracellular Proteases and Their Cellular Regulators

Hideki Hayashi,
Michael Cuddy,
Vincent Chih-Wen Shu,
Kenneth W. Yip,
Charitha Madiraju,
Paul Diaz,
Toshifumi Matsuyama,
Muneshige Kaibara,
Kohtaro Taniyama,
Stefan Vasile

Published: October 30, 2009
https://doi.org/10.1371/journal.pone.0007655

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