The Transcriptional Cofactor Nab2 Is Induced by TGF-β and Suppresses Fibroblast Activation: Physiological Roles and Impaired Expression in Scleroderma

Open Access

Peer-reviewed

Research Article

Swati Bhattacharyya,

Affiliation Division of Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America
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Jun Wei,

Affiliation Division of Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America
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Denisa S. Melichian,

Affiliation Division of Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America
⨯
Jeffrey Milbrandt,

Affiliation Division of Neurology, Washington University School of Medicine, St. Louis, Missouri, United States of America
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Kazuhiko Takehara,

Affiliation Department of Dermatology, Kanazawa University, Kanazawa, Japan
⨯
John Varga

* E-mail: j-varga@northwestern.edu

Affiliation Division of Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America
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Fibroblasts
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Collagens
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Scleroderma
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Biopsy
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Transfection
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Histones
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Small interfering RNA
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Gene expression
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