Phenylalanine-Rich Peptides Potently Bind ESAT6, a Virulence Determinant of Mycobacterium tuberculosis, and Concurrently Affect the Pathogen's Growth

Krishan Kumar; Megha Tharad; Swetha Ganapathy; Geeta Ram; Azeet Narayan; Jameel Ahmad Khan; Rana Pratap; Anamika Ghosh; Sachin Kumar Samuchiwal; Sushil Kumar; Kuhulika Bhalla; Deepti Gupta; Krishnamurthy Natarajan; Yogendra Singh; Anand Ranganathan

doi:10.1371/journal.pone.0007615

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Peer-reviewed

Research Article

Phenylalanine-Rich Peptides Potently Bind ESAT6, a Virulence Determinant of Mycobacterium tuberculosis, and Concurrently Affect the Pathogen's Growth

Krishan Kumar,

Affiliation Recombinant Gene Products Group, International Centre for Genetic Engineering and Biotechnology, New Delhi, India
⨯
Megha Tharad,

Affiliation Recombinant Gene Products Group, International Centre for Genetic Engineering and Biotechnology, New Delhi, India
⨯
Swetha Ganapathy,

Affiliation Recombinant Gene Products Group, International Centre for Genetic Engineering and Biotechnology, New Delhi, India
⨯
Geeta Ram,

Affiliation Recombinant Gene Products Group, International Centre for Genetic Engineering and Biotechnology, New Delhi, India
⨯
Azeet Narayan,

Affiliation Institute of Genomics and Integrative Biology, Delhi, India
⨯
Jameel Ahmad Khan,

Affiliation Institute of Genomics and Integrative Biology, Delhi, India
⨯
Rana Pratap,

Affiliation School of Life Sciences, Jawahar Lal Nehru University, New Delhi, India
⨯
Anamika Ghosh,

Affiliation Recombinant Gene Products Group, International Centre for Genetic Engineering and Biotechnology, New Delhi, India
⨯
Sachin Kumar Samuchiwal,

Affiliation Recombinant Gene Products Group, International Centre for Genetic Engineering and Biotechnology, New Delhi, India
⨯
Sushil Kumar,

Affiliation Recombinant Gene Products Group, International Centre for Genetic Engineering and Biotechnology, New Delhi, India
⨯
Kuhulika Bhalla,

Affiliation Recombinant Gene Products Group, International Centre for Genetic Engineering and Biotechnology, New Delhi, India
⨯
Deepti Gupta,

Affiliation Immunology Group, International Centre for Genetic Engineering and Biotechnology, New Delhi, India
⨯
Krishnamurthy Natarajan,

Affiliation Immunology Group, International Centre for Genetic Engineering and Biotechnology, New Delhi, India
⨯
Yogendra Singh,

Affiliation Institute of Genomics and Integrative Biology, Delhi, India
⨯
Anand Ranganathan

* E-mail: anand@icgeb.res.in

Affiliation Recombinant Gene Products Group, International Centre for Genetic Engineering and Biotechnology, New Delhi, India
⨯

Phenylalanine-Rich Peptides Potently Bind ESAT6, a Virulence Determinant of Mycobacterium tuberculosis, and Concurrently Affect the Pathogen's Growth

Krishan Kumar,
Megha Tharad,
Swetha Ganapathy,
Geeta Ram,
Azeet Narayan,
Jameel Ahmad Khan,
Rana Pratap,
Anamika Ghosh,
Sachin Kumar Samuchiwal,
Sushil Kumar

Published: November 10, 2009
https://doi.org/10.1371/journal.pone.0007615

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