Protective Effects of PARP-1 Knockout on Dyslipidemia-Induced Autonomic and Vascular Dysfunction in ApoE−/− Mice: Effects on eNOS and Oxidative Stress

Chetan P. Hans; Yumei Feng; Amarjit S. Naura; Mourad Zerfaoui; Bashir M. Rezk; Huijing Xia; Alan D. Kaye; Khalid Matrougui; Eric Lazartigues; A. Hamid Boulares

doi:10.1371/journal.pone.0007430

Loading metrics

Open Access

Peer-reviewed

Research Article

Protective Effects of PARP-1 Knockout on Dyslipidemia-Induced Autonomic and Vascular Dysfunction in ApoE^−/− Mice: Effects on eNOS and Oxidative Stress

Chetan P. Hans ,

Contributed equally to this work with: Chetan P. Hans, Yumei Feng

Affiliation Department of Pharmacology and Experimental Therapeutics, Louisiana State University Health Sciences Center, New Orleans, Louisiana, United States of America
⨯
Yumei Feng ,

Contributed equally to this work with: Chetan P. Hans, Yumei Feng

Affiliation Department of Pharmacology and Experimental Therapeutics, Louisiana State University Health Sciences Center, New Orleans, Louisiana, United States of America
⨯
Amarjit S. Naura,

Affiliation Department of Pharmacology and Experimental Therapeutics, Louisiana State University Health Sciences Center, New Orleans, Louisiana, United States of America
⨯
Mourad Zerfaoui,

Affiliation Department of Pharmacology and Experimental Therapeutics, Louisiana State University Health Sciences Center, New Orleans, Louisiana, United States of America
⨯
Bashir M. Rezk,

Affiliation Department of Pharmacology and Experimental Therapeutics, Louisiana State University Health Sciences Center, New Orleans, Louisiana, United States of America
⨯
Huijing Xia,

Affiliation Department of Pharmacology and Experimental Therapeutics, Louisiana State University Health Sciences Center, New Orleans, Louisiana, United States of America
⨯
Alan D. Kaye,

Affiliations Department of Pharmacology and Experimental Therapeutics, Louisiana State University Health Sciences Center, New Orleans, Louisiana, United States of America, Department of Anesthesiology Louisiana State University Health Sciences Center, New Orleans, Louisiana, United States of America
⨯
Khalid Matrougui,

Affiliation Department of Physiology, Tulane University Medical Center, New Orleans, Louisiana, United States of America
⨯
Eric Lazartigues,

Affiliation Department of Pharmacology and Experimental Therapeutics, Louisiana State University Health Sciences Center, New Orleans, Louisiana, United States of America
⨯
A. Hamid Boulares

* E-mail: hboulr@lsuhsc.edu

Affiliation Department of Pharmacology and Experimental Therapeutics, Louisiana State University Health Sciences Center, New Orleans, Louisiana, United States of America
⨯

Protective Effects of PARP-1 Knockout on Dyslipidemia-Induced Autonomic and Vascular Dysfunction in ApoE^−/− Mice: Effects on eNOS and Oxidative Stress

Chetan P. Hans,
Yumei Feng,
Amarjit S. Naura,
Mourad Zerfaoui,
Bashir M. Rezk,
Huijing Xia,
Alan D. Kaye,
Khalid Matrougui,
Eric Lazartigues,
A. Hamid Boulares

Published: October 13, 2009
https://doi.org/10.1371/journal.pone.0007430

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Diet
Is the Subject Area "Diet" applicable to this article?

Thanks for your feedback.
Mouse models
Is the Subject Area "Mouse models" applicable to this article?

Thanks for your feedback.
Deletion mutation
Is the Subject Area "Deletion mutation" applicable to this article?

Thanks for your feedback.
Atherosclerosis
Is the Subject Area "Atherosclerosis" applicable to this article?

Thanks for your feedback.
Cholesterol
Is the Subject Area "Cholesterol" applicable to this article?

Thanks for your feedback.
Dyslipidemia
Is the Subject Area "Dyslipidemia" applicable to this article?

Thanks for your feedback.
Autonomic nervous system
Is the Subject Area "Autonomic nervous system" applicable to this article?

Thanks for your feedback.
Oxidative stress
Is the Subject Area "Oxidative stress" applicable to this article?

Thanks for your feedback.