Post-Training Dephosphorylation of eEF-2 Promotes Protein Synthesis for Memory Consolidation

Heh-In Im; Akira Nakajima; Bo Gong; Xiaoli Xiong; Takayoshi Mamiya; Elliot S. Gershon; Min Zhuo; Ya-Ping Tang

doi:10.1371/journal.pone.0007424

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Peer-reviewed

Research Article

Post-Training Dephosphorylation of eEF-2 Promotes Protein Synthesis for Memory Consolidation

Heh-In Im ,

Contributed equally to this work with: Heh-In Im, Akira Nakajima

Current address: Department of Molecular Therapeutics, Scripps Florida, Jupiter, Florida, United States of America

Affiliations Department of Cell Biology and Anatomy, Louisiana State University Health Sciences Center, New Orleans, Louisiana, United States of America, Neuroscience Center of Excellence, Louisiana State University Health Sciences Center, New Orleans, Louisiana, United States of America
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Akira Nakajima ,

Contributed equally to this work with: Heh-In Im, Akira Nakajima

Current address: Laboratory of Pharmacotherapy, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan

Affiliations Department of Cell Biology and Anatomy, Louisiana State University Health Sciences Center, New Orleans, Louisiana, United States of America, Neuroscience Center of Excellence, Louisiana State University Health Sciences Center, New Orleans, Louisiana, United States of America
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Bo Gong,

Affiliation Department of Physiology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
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Xiaoli Xiong,

Affiliation Department of Cell Biology and Anatomy, Louisiana State University Health Sciences Center, New Orleans, Louisiana, United States of America
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Takayoshi Mamiya,

Affiliations Department of Cell Biology and Anatomy, Louisiana State University Health Sciences Center, New Orleans, Louisiana, United States of America, Neuroscience Center of Excellence, Louisiana State University Health Sciences Center, New Orleans, Louisiana, United States of America
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Elliot S. Gershon,

Affiliation Departments of Psychiatry and Human Genetics, the University of Chicago, Chicago, Illinois, United States of America
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Min Zhuo,

Affiliation Department of Physiology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
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Ya-Ping Tang

* E-mail: ytang1@lsuhsc.edu

Affiliations Department of Cell Biology and Anatomy, Louisiana State University Health Sciences Center, New Orleans, Louisiana, United States of America, Neuroscience Center of Excellence, Louisiana State University Health Sciences Center, New Orleans, Louisiana, United States of America
⨯

Post-Training Dephosphorylation of eEF-2 Promotes Protein Synthesis for Memory Consolidation

Heh-In Im,
Akira Nakajima,
Bo Gong,
Xiaoli Xiong,
Takayoshi Mamiya,
Elliot S. Gershon,
Min Zhuo,
Ya-Ping Tang

Published: October 13, 2009
https://doi.org/10.1371/journal.pone.0007424

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Hippocampus
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Protein synthesis
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Eukaryota
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Memory consolidation
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Translation initiation
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