COMMD1 Promotes pVHL and O2-Independent Proteolysis of HIF-1α via HSP90/70

Bart van de Sluis; Arjan J. Groot; Jeroen Vermeulen; Elsken van der Wall; Paul J. van Diest; Cisca Wijmenga; Leo W. Klomp; Marc Vooijs

doi:10.1371/journal.pone.0007332

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Peer-reviewed

Research Article

COMMD1 Promotes pVHL and O₂-Independent Proteolysis of HIF-1α via HSP90/70

Bart van de Sluis,

Current address: Department of Pathology and Laboratory Medicine, University Medical Center Groningen, Groningen, The Netherlands

Affiliations Complex Genetics Section, DBG-Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands, Laboratory for Metabolic and Endocrine Diseases, University Medical Center Utrecht, Utrecht, The Netherlands, Department of Pathology and Laboratory Medicine, University Medical Center Groningen, Groningen, The Netherlands
⨯
Arjan J. Groot,

Affiliation Department of Pathology, University Medical Center Utrecht, Utrecht, The Netherlands
⨯
Jeroen Vermeulen,

Affiliation Department of Pathology, University Medical Center Utrecht, Utrecht, The Netherlands
⨯
Elsken van der Wall,

Affiliation Department of Internal Medicine, University Medical Center Utrecht, Utrecht, The Netherlands
⨯
Paul J. van Diest,

Affiliation Department of Pathology, University Medical Center Utrecht, Utrecht, The Netherlands
⨯
Cisca Wijmenga,

Affiliations Complex Genetics Section, DBG-Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands, Department of Genetics, University Medical Center Groningen, Groningen, The Netherlands
⨯
Leo W. Klomp,

Affiliation Laboratory for Metabolic and Endocrine Diseases, University Medical Center Utrecht, Utrecht, The Netherlands
⨯
Marc Vooijs

* E-mail: m.vooijs@umcutrecht.nl

Affiliation Department of Pathology, University Medical Center Utrecht, Utrecht, The Netherlands
⨯

COMMD1 Promotes pVHL and O₂-Independent Proteolysis of HIF-1α via HSP90/70

Bart van de Sluis,
Arjan J. Groot,
Jeroen Vermeulen,
Elsken van der Wall,
Paul J. van Diest,
Cisca Wijmenga,
Leo W. Klomp,
Marc Vooijs

Published: October 5, 2009
https://doi.org/10.1371/journal.pone.0007332

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