Splenectomy Normalizes Hematocrit in Murine Polycythemia Vera

Jan-Rung Mo; Anjili Mathur; Minilik Angagaw; Shuxia Zhao; Yuxun Wang; Diana Gargano; Alessandra DiBacco; Eric S. Bachman

doi:10.1371/journal.pone.0007286

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Peer-reviewed

Research Article

Splenectomy Normalizes Hematocrit in Murine Polycythemia Vera

Jan-Rung Mo,

Affiliation Departments of Oncology-Pharmacology, Lab Animal Research and Pharmacology Merck Research Laboratories, Boston, Massachusetts, United States of America
⨯
Anjili Mathur,

Affiliation Departments of Oncology-Pharmacology, Lab Animal Research and Pharmacology Merck Research Laboratories, Boston, Massachusetts, United States of America
⨯
Minilik Angagaw,

Affiliation Departments of Oncology-Pharmacology, Lab Animal Research and Pharmacology Merck Research Laboratories, Boston, Massachusetts, United States of America
⨯
Shuxia Zhao,

Affiliation Departments of Oncology-Pharmacology, Lab Animal Research and Pharmacology Merck Research Laboratories, Boston, Massachusetts, United States of America
⨯
Yuxun Wang,

Affiliation Departments of Oncology-Pharmacology, Lab Animal Research and Pharmacology Merck Research Laboratories, Boston, Massachusetts, United States of America
⨯
Diana Gargano,

Affiliation Departments of Oncology-Pharmacology, Lab Animal Research and Pharmacology Merck Research Laboratories, Boston, Massachusetts, United States of America
⨯
Alessandra DiBacco,

Affiliation Departments of Oncology-Pharmacology, Lab Animal Research and Pharmacology Merck Research Laboratories, Boston, Massachusetts, United States of America
⨯
Eric S. Bachman

* E-mail: eric.bachman@bmc.org

Current address: Section in Endocrinology, Diabetes and Nutrition, Boston University School of Medicine, Boston, Massachusetts, United States of America

Affiliation Departments of Oncology-Pharmacology, Lab Animal Research and Pharmacology Merck Research Laboratories, Boston, Massachusetts, United States of America
⨯

Splenectomy Normalizes Hematocrit in Murine Polycythemia Vera

Jan-Rung Mo,
Anjili Mathur,
Minilik Angagaw,
Shuxia Zhao,
Yuxun Wang,
Diana Gargano,
Alessandra DiBacco,
Eric S. Bachman

Published: September 30, 2009
https://doi.org/10.1371/journal.pone.0007286

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Spleen
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Hematocrit
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Splenectomy
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Polycythemia
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Mouse models
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Bone marrow cells
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Fibrosis
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