Inducible Bronchus-Associated Lymphoid Tissue Elicited by a Protein Cage Nanoparticle Enhances Protection in Mice against Diverse Respiratory Viruses

James A. Wiley; Laura E. Richert; Steve D. Swain; Ann Harmsen; Dale L. Barnard; Troy D. Randall; Mark Jutila; Trevor Douglas; Chris Broomell; Mark Young; Allen Harmsen

doi:10.1371/journal.pone.0007142

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Open Access

Peer-reviewed

Research Article

Inducible Bronchus-Associated Lymphoid Tissue Elicited by a Protein Cage Nanoparticle Enhances Protection in Mice against Diverse Respiratory Viruses

James A. Wiley ,

* E-mail: jwiley@montana.edu

Affiliation Department of Veterinary Molecular Biology, Montana State University, Bozeman, Montana, United States of America
⨯
Laura E. Richert,

Affiliation Department of Veterinary Molecular Biology, Montana State University, Bozeman, Montana, United States of America
⨯
Steve D. Swain,

Affiliation Department of Veterinary Molecular Biology, Montana State University, Bozeman, Montana, United States of America
⨯
Ann Harmsen,

Affiliation Department of Veterinary Molecular Biology, Montana State University, Bozeman, Montana, United States of America
⨯
Dale L. Barnard,

Affiliation Institute for Antiviral Research, Utah State University, Logan, Utah, United States of America
⨯
Troy D. Randall,

Affiliation Division of Allergy, Immunology and Rheumatology, University of Rochester Medical Center, Rochester, New York, United States of America
⨯
Mark Jutila,

Affiliation Department of Veterinary Molecular Biology, Montana State University, Bozeman, Montana, United States of America
⨯
Trevor Douglas,

Affiliations Center for Bio-Inspired Nanomaterials, Montana State University, Bozeman, Montana, United States of America, Department of Chemistry and Biochemistry, Montana State University, Bozeman, Montana, United States of America
⨯
Chris Broomell,

Affiliations Center for Bio-Inspired Nanomaterials, Montana State University, Bozeman, Montana, United States of America, Department of Chemistry and Biochemistry, Montana State University, Bozeman, Montana, United States of America
⨯
Mark Young,

Affiliations Center for Bio-Inspired Nanomaterials, Montana State University, Bozeman, Montana, United States of America, Department of Plant Sciences, Montana State University, Bozeman, Montana, United States of America
⨯
Allen Harmsen

Affiliation Department of Veterinary Molecular Biology, Montana State University, Bozeman, Montana, United States of America
⨯

Inducible Bronchus-Associated Lymphoid Tissue Elicited by a Protein Cage Nanoparticle Enhances Protection in Mice against Diverse Respiratory Viruses

James A. Wiley,
Laura E. Richert,
Steve D. Swain,
Ann Harmsen,
Dale L. Barnard,
Troy D. Randall,
Mark Jutila,
Trevor Douglas,
Chris Broomell,
Mark Young

Published: September 23, 2009
https://doi.org/10.1371/journal.pone.0007142

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