In Vivo Turnover of Tau and APP Metabolites in the Brains of Wild-Type and Tg2576 Mice: Greater Stability of sAPP in the β-Amyloid Depositing Mice

Jose Morales-Corraliza; Matthew J. Mazzella; Jason D. Berger; Nicole S. Diaz; Jennifer H. K. Choi; Efrat Levy; Yasuji Matsuoka; Emmanuel Planel; Paul M. Mathews

doi:10.1371/journal.pone.0007134

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Peer-reviewed

Research Article

In Vivo Turnover of Tau and APP Metabolites in the Brains of Wild-Type and Tg2576 Mice: Greater Stability of sAPP in the β-Amyloid Depositing Mice

Jose Morales-Corraliza ,

* E-mail: jmorales-corraliza@nki.rfmh.org (JMC); mathews@nki.rfmh.org (PMM)

Affiliations Nathan Kline Institute for Psychiatric Research, Orangeburg, New York, United States of America, New York University School of Medicine, Orangeburg, New York, United States of America
⨯
Matthew J. Mazzella,

Affiliation Nathan Kline Institute for Psychiatric Research, Orangeburg, New York, United States of America
⨯
Jason D. Berger,

Affiliation Nathan Kline Institute for Psychiatric Research, Orangeburg, New York, United States of America
⨯
Nicole S. Diaz,

Affiliation Nathan Kline Institute for Psychiatric Research, Orangeburg, New York, United States of America
⨯
Jennifer H. K. Choi,

Affiliations Nathan Kline Institute for Psychiatric Research, Orangeburg, New York, United States of America, New York University School of Medicine, Orangeburg, New York, United States of America
⨯
Efrat Levy,

Affiliations Nathan Kline Institute for Psychiatric Research, Orangeburg, New York, United States of America, New York University School of Medicine, Orangeburg, New York, United States of America
⨯
Yasuji Matsuoka,

Current address: Neurodegeneration Research, GlaxoSmithKline, Shanghai, China

Affiliation Department of Neurology, Georgetown University Medical Center, Washington, D. C, United States of America
⨯
Emmanuel Planel,

Affiliation Centre Hospitalier de l'Université Laval, Neurosciences, Québec, Canada
⨯
Paul M. Mathews

* E-mail: jmorales-corraliza@nki.rfmh.org (JMC); mathews@nki.rfmh.org (PMM)

Affiliations Nathan Kline Institute for Psychiatric Research, Orangeburg, New York, United States of America, New York University School of Medicine, Orangeburg, New York, United States of America
⨯

In Vivo Turnover of Tau and APP Metabolites in the Brains of Wild-Type and Tg2576 Mice: Greater Stability of sAPP in the β-Amyloid Depositing Mice

Jose Morales-Corraliza,
Matthew J. Mazzella,
Jason D. Berger,
Nicole S. Diaz,
Jennifer H. K. Choi,
Efrat Levy,
Yasuji Matsuoka,
Emmanuel Planel,
Paul M. Mathews

Published: September 22, 2009
https://doi.org/10.1371/journal.pone.0007134

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