Oxidative Inactivation of Mitochondrial Aconitase Results in Iron and H2O2-Mediated Neurotoxicity in Rat Primary Mesencephalic Cultures

Open Access

Peer-reviewed

Research Article

Oxidative Inactivation of Mitochondrial Aconitase Results in Iron and H₂O₂-Mediated Neurotoxicity in Rat Primary Mesencephalic Cultures

David Cantu,

Affiliation Neuroscience Program, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado, United States of America
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Jerome Schaack,

Affiliation Department of Microbiology, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado, United States of America
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Manisha Patel

* E-mail: manisha.patel@ucdenver.edu

Affiliations Neuroscience Program, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado, United States of America, Department of Pharmaceutical Sciences, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado, United States of America
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Mitochondria
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Neuronal death
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Cell death
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Midbrain
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Recombinase polymerase amplification
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Astrocytes
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Catalases
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Oxidative stress
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