Overexpression of Transcription Factor Sp1 Leads to Gene Expression Perturbations and Cell Cycle Inhibition

Emmanuelle Deniaud; Joël Baguet; Roxane Chalard; Bariza Blanquier; Lilia Brinza; Julien Meunier; Marie-Cécile Michallet; Aurélie Laugraud; Claudette Ah-Soon; Anne Wierinckx; Marc Castellazzi; Joël Lachuer; Christian Gautier; Jacqueline Marvel; Yann Leverrier

doi:10.1371/journal.pone.0007035

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Open Access

Peer-reviewed

Research Article

Overexpression of Transcription Factor Sp1 Leads to Gene Expression Perturbations and Cell Cycle Inhibition

Emmanuelle Deniaud,

Affiliations Inserm, U851, Lyon, France, Université Lyon1, IFR128, Lyon, France, Université de Lyon, Lyon, France
⨯
Joël Baguet,

Affiliations Inserm, U851, Lyon, France, Université Lyon1, IFR128, Lyon, France, Université de Lyon, Lyon, France
⨯
Roxane Chalard,

Affiliations Inserm, U851, Lyon, France, Université Lyon1, IFR128, Lyon, France, Université de Lyon, Lyon, France
⨯
Bariza Blanquier,

Affiliations Université Lyon1, IFR128, Lyon, France, Université de Lyon, Lyon, France
⨯
Lilia Brinza,

Affiliations Inserm, U851, Lyon, France, Université Lyon1, IFR128, Lyon, France, Université de Lyon, Lyon, France
⨯
Julien Meunier,

Affiliations Inserm, U851, Lyon, France, Université Lyon1, IFR128, Lyon, France, Université de Lyon, Lyon, France
⨯
Marie-Cécile Michallet,

Affiliations Inserm, U851, Lyon, France, Université Lyon1, IFR128, Lyon, France, Université de Lyon, Lyon, France
⨯
Aurélie Laugraud,

Affiliations Université de Lyon, Lyon, France, PRABI, Villeurbanne, France
⨯
Claudette Ah-Soon,

Affiliations Université de Lyon, Lyon, France, PRABI, Villeurbanne, France
⨯
Anne Wierinckx,

Affiliation ProfileXpert, Bron, France
⨯
Marc Castellazzi,

Affiliations Université Lyon1, IFR128, Lyon, France, Université de Lyon, Lyon, France, Inserm, U758, Ecole Normale Supérieure de Lyon, Lyon, France
⨯
Joël Lachuer,

Affiliation ProfileXpert, Bron, France
⨯
Christian Gautier,

Affiliations Université de Lyon, Lyon, France, PRABI, Villeurbanne, France
⨯
Jacqueline Marvel ,

Contributed equally to this work with: Jacqueline Marvel, Yann Leverrier

* E-mail: jacqueline.marvel@inserm.fr (JM); yann.leverrier@inserm.fr (YL)

Affiliations Inserm, U851, Lyon, France, Université Lyon1, IFR128, Lyon, France, Université de Lyon, Lyon, France
⨯
Yann Leverrier

Contributed equally to this work with: Jacqueline Marvel, Yann Leverrier

* E-mail: jacqueline.marvel@inserm.fr (JM); yann.leverrier@inserm.fr (YL)

Affiliations Inserm, U851, Lyon, France, Université Lyon1, IFR128, Lyon, France, Université de Lyon, Lyon, France
⨯

Overexpression of Transcription Factor Sp1 Leads to Gene Expression Perturbations and Cell Cycle Inhibition

Emmanuelle Deniaud,
Joël Baguet,
Roxane Chalard,
Bariza Blanquier,
Lilia Brinza,
Julien Meunier,
Marie-Cécile Michallet,
Aurélie Laugraud,
Claudette Ah-Soon,
Anne Wierinckx

Published: September 15, 2009
https://doi.org/10.1371/journal.pone.0007035

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Gene expression
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Cell cycle and cell division
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Apoptosis
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Gene regulation
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DNA transcription
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Transcription factors
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Cyclins
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Doxycycline
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