ZNF93 Increases Resistance to ET-743 (Trabectedin; Yondelis®) and PM00104 (Zalypsis®) in Human Cancer Cell Lines

Open Access

Peer-reviewed

Research Article

Zhenfeng Duan ,

* E-mail: zduan@partners.org

Affiliation Sarcoma Biology Laboratory, Center for Sarcoma and Connective Tissue Oncology, Massachusetts General Hospital, Boston, Massachusetts, United States of America
⨯
Edwin Choy,

Affiliation Cancer Center/Hematology Oncology, Massachusetts General Hospital, Boston, Massachusetts, United States of America
⨯
David Harmon,

Affiliation Cancer Center/Hematology Oncology, Massachusetts General Hospital, Boston, Massachusetts, United States of America
⨯
Cao Yang,

Affiliation Sarcoma Biology Laboratory, Center for Sarcoma and Connective Tissue Oncology, Massachusetts General Hospital, Boston, Massachusetts, United States of America
⨯
Keinosuke Ryu,

Affiliation Sarcoma Biology Laboratory, Center for Sarcoma and Connective Tissue Oncology, Massachusetts General Hospital, Boston, Massachusetts, United States of America
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Joseph Schwab,

Affiliation Sarcoma Biology Laboratory, Center for Sarcoma and Connective Tissue Oncology, Massachusetts General Hospital, Boston, Massachusetts, United States of America
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Henry Mankin,

Affiliation Sarcoma Biology Laboratory, Center for Sarcoma and Connective Tissue Oncology, Massachusetts General Hospital, Boston, Massachusetts, United States of America
⨯
Francis J. Hornicek

Affiliation Sarcoma Biology Laboratory, Center for Sarcoma and Connective Tissue Oncology, Massachusetts General Hospital, Boston, Massachusetts, United States of America
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Small interfering RNA
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Gene expression
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Reverse transcriptase-polymerase chain reaction
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Transfection
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Zinc finger domains
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Genetic loci
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Gene regulation
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Ovarian cancer
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