Loss of Anti-Bax Function in Gerstmann-Sträussler-Scheinker Syndrome-Associated Prion Protein Mutants

Open Access

Peer-reviewed

Research Article

Julie Jodoin,

Affiliations Bloomfield Center for Research in Aging, Lady Davis Institute for Medical Research, Sir Mortimer B. Davis Jewish General Hospital, Montréal, Canada, Department of Neurology and Neurosurgery, McGill University, Montréal, Canada
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Micheal Misiewicz,

Affiliation Bloomfield Center for Research in Aging, Lady Davis Institute for Medical Research, Sir Mortimer B. Davis Jewish General Hospital, Montréal, Canada
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Priya Makhijani,

Affiliation Bloomfield Center for Research in Aging, Lady Davis Institute for Medical Research, Sir Mortimer B. Davis Jewish General Hospital, Montréal, Canada
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Paresa N. Giannopoulos,

Affiliation Bloomfield Center for Research in Aging, Lady Davis Institute for Medical Research, Sir Mortimer B. Davis Jewish General Hospital, Montréal, Canada
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Jennifer Hammond,

Affiliation Bloomfield Center for Research in Aging, Lady Davis Institute for Medical Research, Sir Mortimer B. Davis Jewish General Hospital, Montréal, Canada
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Cynthia G. Goodyer,

Affiliation Department of Pediatrics, McGill University, Montréal, Canada
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Andréa C. LeBlanc

* E-mail: andrea.leblanc@mcgill.ca.

Affiliations Bloomfield Center for Research in Aging, Lady Davis Institute for Medical Research, Sir Mortimer B. Davis Jewish General Hospital, Montréal, Canada, Department of Neurology and Neurosurgery, McGill University, Montréal, Canada
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Chromatin
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Transfection
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Point mutation
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Gerstmann-Straussler-Scheinker disease
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Neuronal death
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Neurons
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Nuclear membrane
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Apoptosis
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