Homeodomain Interacting Protein Kinase 2 Activation Compromises Endothelial Cell Response to Laminar Flow: Protective Role of p21waf1,cip1,sdi1

Open Access

Peer-reviewed

Research Article

Homeodomain Interacting Protein Kinase 2 Activation Compromises Endothelial Cell Response to Laminar Flow: Protective Role of p21^{waf1,cip1,sdi1}

Stefania Mattiussi,

Affiliation Laboratorio di Patologia Vascolare, Istituto Dermopatico dell' Immacolata, Roma, Italy
⨯
Chiara Lazzari,

Affiliation Laboratorio di Oncogenesi Molecolare, Dipartimento di Oncologia Sperimentale, Istituto Regina Elena, Roma, Italy
⨯
Silvia Truffa,

Current address: San Diego State Heart Institute, San Diego State University, San Diego, California, United States of America

Affiliation Laboratorio di Patologia Vascolare, Istituto Dermopatico dell' Immacolata, Roma, Italy
⨯
Annalisa Antonini,

Affiliation Laboratorio di Patologia Vascolare, Istituto Dermopatico dell' Immacolata, Roma, Italy
⨯
Silvia Soddu,

Affiliation Laboratorio di Oncogenesi Molecolare, Dipartimento di Oncologia Sperimentale, Istituto Regina Elena, Roma, Italy
⨯
Maurizio C. Capogrossi,

Affiliation Laboratorio di Patologia Vascolare, Istituto Dermopatico dell' Immacolata, Roma, Italy
⨯
Carlo Gaetano

* E-mail: gaetano@idi.it

Affiliation Laboratorio di Patologia Vascolare, Istituto Dermopatico dell' Immacolata, Roma, Italy
⨯

Endothelial cells
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Laminar flow
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Cell death
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Nitric oxide
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Protein kinase signaling cascade
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Phosphorylation
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Apoptosis
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DNA damage
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