Tolerance Induction to Cytoplasmic β-Galactosidase by Hepatic AAV Gene Transfer — Implications for Antigen Presentation and Immunotoxicity

Open Access

Peer-reviewed

Research Article

Ashley T. Martino ,

Contributed equally to this work with: Ashley T. Martino, Sushrusha Nayak

Affiliation Department of Pediatrics, University of Florida, Gainesville, Florida, United States of America
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Sushrusha Nayak ,

Contributed equally to this work with: Ashley T. Martino, Sushrusha Nayak

Affiliation Department of Pediatrics, University of Florida, Gainesville, Florida, United States of America
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Brad E. Hoffman,

Affiliation Department of Pediatrics, University of Florida, Gainesville, Florida, United States of America
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Mario Cooper,

Affiliation Department of Pediatrics, University of Florida, Gainesville, Florida, United States of America
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Gongxian Liao,

Affiliation Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America
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David M. Markusic,

Affiliation Department of Pediatrics, University of Florida, Gainesville, Florida, United States of America
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Barry J. Byrne,

Affiliation Department of Pediatrics, University of Florida, Gainesville, Florida, United States of America
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Cox Terhorst,

Affiliation Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America
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Roland W. Herzog

* E-mail: rherzog@ufl.edu

Affiliation Department of Pediatrics, University of Florida, Gainesville, Florida, United States of America
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Gene transfer
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T cells
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Hepatocytes
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Inflammation
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Cytotoxic T cells
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Regulatory T cells
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Enzyme-linked immunoassays
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Viral vectors
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