A Novel and Efficient Gene Transfer Strategy Reduces Glial Reactivity and Improves Neuronal Survival and Axonal Growth In Vitro

Mathieu Desclaux; Marisa Teigell; Lahouari Amar; Roland Vogel; Minerva Gimenez y Ribotta; Alain Privat; Jacques Mallet

doi:10.1371/journal.pone.0006227

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Peer-reviewed

Research Article

A Novel and Efficient Gene Transfer Strategy Reduces Glial Reactivity and Improves Neuronal Survival and Axonal Growth In Vitro

Mathieu Desclaux,

Affiliation Biotechnology and Biotherapy, Centre de Recherche de l'Institut du Cerveau et de la Moelle Epiniere, Centre National de la Recherche Scientifique (CNRS) UMR 7225, Institut National de la Santé et de la Recherche Médicale (INSERM) UMRS 975, Université Pierre et Marie Curie (UPMC) - Hôpital de la Pitié Salpêtrière, Paris, France
⨯
Marisa Teigell,

Affiliation NEUREVA-inc., Montpellier, France
⨯
Lahouari Amar,

Affiliation Biotechnology and Biotherapy, Centre de Recherche de l'Institut du Cerveau et de la Moelle Epiniere, Centre National de la Recherche Scientifique (CNRS) UMR 7225, Institut National de la Santé et de la Recherche Médicale (INSERM) UMRS 975, Université Pierre et Marie Curie (UPMC) - Hôpital de la Pitié Salpêtrière, Paris, France
⨯
Roland Vogel,

Affiliation Biotechnology and Biotherapy, Centre de Recherche de l'Institut du Cerveau et de la Moelle Epiniere, Centre National de la Recherche Scientifique (CNRS) UMR 7225, Institut National de la Santé et de la Recherche Médicale (INSERM) UMRS 975, Université Pierre et Marie Curie (UPMC) - Hôpital de la Pitié Salpêtrière, Paris, France
⨯
Minerva Gimenez y Ribotta,

Affiliation Consejo Superior de Investigationes Cientifícas (CSIC), Universidad Miguel Hernández (UMH), Instituto de Neurociencias de Alicante, Sant Joan D'Alacant Nacional, España
⨯
Alain Privat ,

* E-mail: privat@univ-montp2.fr

Affiliation Institut National de la Santé et de la Recherche Médicale (INSERM) U583, Physiopathologie et Thérapie des Déficits Sensoriels et Moteurs, Institut des Neurosciences de Montpellier (INM), Université Montpellier 2, Montpellier, France
⨯
Jacques Mallet

Affiliation Biotechnology and Biotherapy, Centre de Recherche de l'Institut du Cerveau et de la Moelle Epiniere, Centre National de la Recherche Scientifique (CNRS) UMR 7225, Institut National de la Santé et de la Recherche Médicale (INSERM) UMRS 975, Université Pierre et Marie Curie (UPMC) - Hôpital de la Pitié Salpêtrière, Paris, France
⨯

A Novel and Efficient Gene Transfer Strategy Reduces Glial Reactivity and Improves Neuronal Survival and Axonal Growth In Vitro

Mathieu Desclaux,
Marisa Teigell,
Lahouari Amar,
Roland Vogel,
Minerva Gimenez y Ribotta,
Alain Privat,
Jacques Mallet

Published: July 14, 2009
https://doi.org/10.1371/journal.pone.0006227

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