A Novel In Vitro Multiple-Stress Dormancy Model for Mycobacterium tuberculosis Generates a Lipid-Loaded, Drug-Tolerant, Dormant Pathogen

Chirajyoti Deb; Chang-Muk Lee; Vinod S. Dubey; Jaiyanth Daniel; Bassam Abomoelak; Tatiana D. Sirakova; Santosh Pawar; Linda Rogers; Pappachan E. Kolattukudy

doi:10.1371/journal.pone.0006077

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Open Access

Peer-reviewed

Research Article

A Novel In Vitro Multiple-Stress Dormancy Model for Mycobacterium tuberculosis Generates a Lipid-Loaded, Drug-Tolerant, Dormant Pathogen

Chirajyoti Deb,

Affiliation Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, Florida, United States of America
⨯
Chang-Muk Lee,

Affiliation Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, Florida, United States of America
⨯
Vinod S. Dubey,

Affiliation Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, Florida, United States of America
⨯
Jaiyanth Daniel,

Affiliation Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, Florida, United States of America
⨯
Bassam Abomoelak,

Affiliation Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, Florida, United States of America
⨯
Tatiana D. Sirakova,

Affiliation Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, Florida, United States of America
⨯
Santosh Pawar,

Affiliation Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, Florida, United States of America
⨯
Linda Rogers,

Affiliation Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, Florida, United States of America
⨯
Pappachan E. Kolattukudy

* E-mail: pk@mail.ucf.edu

Affiliation Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, Florida, United States of America
⨯

A Novel In Vitro Multiple-Stress Dormancy Model for Mycobacterium tuberculosis Generates a Lipid-Loaded, Drug-Tolerant, Dormant Pathogen

Chirajyoti Deb,
Chang-Muk Lee,
Vinod S. Dubey,
Jaiyanth Daniel,
Bassam Abomoelak,
Tatiana D. Sirakova,
Santosh Pawar,
Linda Rogers,
Pappachan E. Kolattukudy

Published: June 29, 2009
https://doi.org/10.1371/journal.pone.0006077

Reader Comments (3)

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26 Nov 2009
18:01 GMT
Most Recent

Singing own praise!! Posted by NiyazAhmed on 26 Nov 2009 at 18:01 GMT
1 Response

26 Nov 2009
17:59 GMT
Most Recent

Very important piece of work Posted by drchiradeb on 20 Nov 2009 at 19:10 GMT

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Mycobacterium tuberculosis
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Lipids
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