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Open Access
Peer-reviewed
Research Article
Rapid Evolution of Virulence and Drug Resistance in the Emerging Zoonotic Pathogen Streptococcus suis
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Matthew T. G. Holden ,
* E-mail: mh3@sanger.ac.uk
Affiliation The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom
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Heidi Hauser,
Affiliation The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom
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Mandy Sanders,
Affiliation The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom
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Thi Hoa Ngo,
Affiliation Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Viet Nam
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Inna Cherevach,
Affiliation The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom
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Ann Cronin,
Affiliation The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom
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Ian Goodhead,
Current address: School of Biological Sciences, University of Liverpool, Liverpool, United Kingdom
Affiliation The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom
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Karen Mungall,
Affiliation The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom
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Michael A. Quail,
Affiliation The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom
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Claire Price,
Affiliation The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom
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Ester Rabbinowitsch,
Affiliation The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom
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Sarah Sharp,
Affiliation The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom
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Nicholas J. Croucher,
Affiliation The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom
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Tran Bich Chieu,
Affiliation Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Viet Nam
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Nguyen Thi Hoang Mai,
Affiliation Hospital for Tropical Diseases, Ho Chi Minh City, Viet Nam
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To Song Diep,
Affiliation Hospital for Tropical Diseases, Ho Chi Minh City, Viet Nam
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Nguyen Tran Chinh,
Affiliation Hospital for Tropical Diseases, Ho Chi Minh City, Viet Nam
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Michael Kehoe,
Affiliation Institute for Cell and Molecular Biosciences, The Medical School, University of Newcastle upon Tyne, Newcastle upon Tyne, United Kingdom
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James A. Leigh,
Affiliation The School of Veterinary Medicine and Science, The University of Nottingham, Sutton Bonington Campus, Sutton Bonington, United Kingdom
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Philip N. Ward,
Affiliation Nuffield Department of Clinical Laboratory Sciences, Oxford University, John Radcliffe Hospital, Headington, United Kingdom
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Christopher G. Dowson,
Affiliation Department of Biological Sciences, University of Warwick, Coventry, United Kingdom
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Adrian M. Whatmore,
Current address: Veterinary Laboratories Agency, Weybridge, United Kingdom
Affiliation Department of Biological Sciences, University of Warwick, Coventry, United Kingdom
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Neil Chanter,
Affiliation Centre for Preventative Medicine, Animal Health Trust, Newmarket, United Kingdom
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Pernille Iversen,
Affiliation Department of Biology, University of Copenhagen, Copenhagen, Denmark
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Marcelo Gottschalk,
Affiliation Groupe de recherche sur les maladies infectieuses du porc (GREMIP), Université de Montréal, Montréal, Québec, Canada
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Josh D. Slater,
Affiliation Royal Veterinary College, Hatfield, United Kingdom
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Hilde E. Smith,
Affiliation Animal Sciences Group (ASG), Wageningen UR, UR, Lelystad, The Netherlands
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Brian G. Spratt,
Affiliation Department of Infectious Disease Epidemiology, Imperial College, London, United Kingdom
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Jianguo Xu,
Affiliation State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Communicable Disease Control and Prevention, China CDC, Beijing, China
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Changyun Ye,
Affiliation State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Communicable Disease Control and Prevention, China CDC, Beijing, China
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Stephen Bentley,
Affiliation The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom
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Barclay G. Barrell,
Affiliation The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom
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Constance Schultsz,
Affiliations Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Viet Nam, Academic Medical Center-Center for Poverty-Related Communicable Diseases, University of Amsterdam, Amsterdam, The Netherlands
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Duncan J. Maskell,
Affiliation Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom
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Julian Parkhill
Affiliation The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom
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Rapid Evolution of Virulence and Drug Resistance in the Emerging Zoonotic Pathogen Streptococcus suis
- Matthew T. G. Holden,
- Heidi Hauser,
- Mandy Sanders,
- Thi Hoa Ngo,
- Inna Cherevach,
- Ann Cronin,
- Ian Goodhead,
- Karen Mungall,
- Michael A. Quail,
- Claire Price
- Published: July 15, 2009
- https://doi.org/10.1371/journal.pone.0006072