Increased Sensitivity to Thermal Pain Following a Single Opiate Dose Is Influenced by the COMT val158met Polymorphism

Open Access

Peer-reviewed

Research Article

Increased Sensitivity to Thermal Pain Following a Single Opiate Dose Is Influenced by the COMT val¹⁵⁸met Polymorphism

Karin B. Jensen ,

* E-mail: Karin.B.Jensen@ki.se

Affiliation Osher Center For Integrative Medicine, Stockholm Brain Institute, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
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Tina B. Lonsdorf,

Affiliation Osher Center For Integrative Medicine, Stockholm Brain Institute, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
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Martin Schalling,

Affiliation Centre for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden
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Eva Kosek,

Affiliation Osher Center For Integrative Medicine, Stockholm Brain Institute, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
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Martin Ingvar

Affiliation Osher Center For Integrative Medicine, Stockholm Brain Institute, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
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Pain
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Opioids
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Pain sensation
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Hyperalgesia
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Alleles
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Intravenous injections
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Receptor potentials
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Homozygosity
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