NSOM/QD-Based Direct Visualization of CD3-Induced and CD28-Enhanced Nanospatial Coclustering of TCR and Coreceptor in Nanodomains in T Cell Activation

Liyun Zhong; Gucheng Zeng; Xiaoxu Lu; Richard C. Wang; Guangming Gong; Lin Yan; Dan Huang; Zheng W. Chen

doi:10.1371/journal.pone.0005945

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Open Access

Peer-reviewed

Research Article

NSOM/QD-Based Direct Visualization of CD3-Induced and CD28-Enhanced Nanospatial Coclustering of TCR and Coreceptor in Nanodomains in T Cell Activation

Liyun Zhong ,

Contributed equally to this work with: Liyun Zhong, Gucheng Zeng

Affiliation Department of Microbiology and Immunology, Center for Primate Biomedical Research, University of Illinois College of Medicine, Chicago, Illinois, United States of America
⨯
Gucheng Zeng ,

Contributed equally to this work with: Liyun Zhong, Gucheng Zeng

Affiliation Department of Microbiology and Immunology, Center for Primate Biomedical Research, University of Illinois College of Medicine, Chicago, Illinois, United States of America
⨯
Xiaoxu Lu,

Affiliation School for Information and Optoelectronic Engineering, South China Normal University, Guangzhou, Guangdong, China
⨯
Richard C. Wang,

Affiliation Department of Microbiology and Immunology, Center for Primate Biomedical Research, University of Illinois College of Medicine, Chicago, Illinois, United States of America
⨯
Guangming Gong,

Affiliation Department of Microbiology and Immunology, Center for Primate Biomedical Research, University of Illinois College of Medicine, Chicago, Illinois, United States of America
⨯
Lin Yan,

Affiliation Department of Microbiology and Immunology, Center for Primate Biomedical Research, University of Illinois College of Medicine, Chicago, Illinois, United States of America
⨯
Dan Huang,

Affiliation Department of Microbiology and Immunology, Center for Primate Biomedical Research, University of Illinois College of Medicine, Chicago, Illinois, United States of America
⨯
Zheng W. Chen

* E-mail: zchen@uic.edu

Affiliation Department of Microbiology and Immunology, Center for Primate Biomedical Research, University of Illinois College of Medicine, Chicago, Illinois, United States of America
⨯

NSOM/QD-Based Direct Visualization of CD3-Induced and CD28-Enhanced Nanospatial Coclustering of TCR and Coreceptor in Nanodomains in T Cell Activation

Liyun Zhong,
Gucheng Zeng,
Xiaoxu Lu,
Richard C. Wang,
Guangming Gong,
Lin Yan,
Dan Huang,
Zheng W. Chen

Published: June 17, 2009
https://doi.org/10.1371/journal.pone.0005945

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12 Mar 2010
01:11 GMT
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Publisher's Note: Correction to Figure S6 legend Posted by PLOS_ONE_Group on 12 Mar 2010 at 01:11 GMT
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12 Mar 2010
01:06 GMT
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Publisher's Note: Correction to Figure S7 Posted by PLOS_ONE_Group on 12 Mar 2010 at 01:06 GMT
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10 Mar 2010
02:36 GMT
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Fig.S1 has a doc suffix Posted by lyzhong on 10 Mar 2010 at 02:36 GMT

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T cells
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Cytotoxic T cells
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CD coreceptors
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