MicroRNA Expression Profiling in Mild Asthmatic Human Airways and Effect of Corticosteroid Therapy

Andrew E. Williams; Hanna Larner-Svensson; Mark M. Perry; Gaynor A. Campbell; Sarah E. Herrick; Ian M. Adcock; Jonas S. Erjefalt; Kian Fan Chung; Mark A. Lindsay

doi:10.1371/journal.pone.0005889

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Open Access

Peer-reviewed

Research Article

MicroRNA Expression Profiling in Mild Asthmatic Human Airways and Effect of Corticosteroid Therapy

Andrew E. Williams ,

* E-mail: a.williams@imperial.ac.uk (AEW); mark.lindsay@manchester.ac.uk (MAL)

Affiliations Biopharmaceutics Research Group, National Heart and Lung Institute, Imperial College, London, United Kingdom, Airways Disease, National Heart and Lung Institute, Imperial College, London, United Kingdom
⨯
Hanna Larner-Svensson,

Affiliations Biopharmaceutics Research Group, National Heart and Lung Institute, Imperial College, London, United Kingdom, Airways Disease, National Heart and Lung Institute, Imperial College, London, United Kingdom
⨯
Mark M. Perry,

Affiliations Biopharmaceutics Research Group, National Heart and Lung Institute, Imperial College, London, United Kingdom, Airways Disease, National Heart and Lung Institute, Imperial College, London, United Kingdom
⨯
Gaynor A. Campbell,

Affiliation Respiratory Translational Research Facility, Wythenshawe Hospital, School of Translational Sciences, University of Manchester, Manchester, United Kingdom
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Sarah E. Herrick,

Affiliation Respiratory Translational Research Facility, Wythenshawe Hospital, School of Translational Sciences, University of Manchester, Manchester, United Kingdom
⨯
Ian M. Adcock,

Affiliation Airways Disease, National Heart and Lung Institute, Imperial College, London, United Kingdom
⨯
Jonas S. Erjefalt,

Affiliation Department of Experimental Medical Science, Division of Vascular and Airway Research, Lund University, Lund, Sweden
⨯
Kian Fan Chung,

Affiliation Airways Disease, National Heart and Lung Institute, Imperial College, London, United Kingdom
⨯
Mark A. Lindsay

* E-mail: a.williams@imperial.ac.uk (AEW); mark.lindsay@manchester.ac.uk (MAL)

Affiliations Biopharmaceutics Research Group, National Heart and Lung Institute, Imperial College, London, United Kingdom, Airways Disease, National Heart and Lung Institute, Imperial College, London, United Kingdom, Department of Experimental Medical Science, Division of Vascular and Airway Research, Lund University, Lund, Sweden
⨯

MicroRNA Expression Profiling in Mild Asthmatic Human Airways and Effect of Corticosteroid Therapy

Andrew E. Williams,
Hanna Larner-Svensson,
Mark M. Perry,
Gaynor A. Campbell,
Sarah E. Herrick,
Ian M. Adcock,
Jonas S. Erjefalt,
Kian Fan Chung,
Mark A. Lindsay

Published: June 12, 2009
https://doi.org/10.1371/journal.pone.0005889

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MicroRNAs
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Asthma
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Biopsy
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Corticosteroid therapy
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Transcription factors
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Gene expression
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Epithelial cells
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