STAT1 Pathway Mediates Amplification of Metastatic Potential and Resistance to Therapy

Nikolai N. Khodarev; Paul Roach; Sean P. Pitroda; Daniel W. Golden; Mihir Bhayani; Michael Y. Shao; Thomas E. Darga; Mara G. Beveridge; Ravi F. Sood; Harold G. Sutton; Michael A. Beckett; Helena J. Mauceri; Mitchell C. Posner; Ralph R. Weichselbaum

doi:10.1371/journal.pone.0005821

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Open Access

Peer-reviewed

Research Article

STAT1 Pathway Mediates Amplification of Metastatic Potential and Resistance to Therapy

Nikolai N. Khodarev ,

Contributed equally to this work with: Nikolai N. Khodarev, Paul Roach

Affiliation Department of Radiation and Cellular Oncology, University of Chicago, Chicago, Illinois, United States of America
⨯
Paul Roach ,

Contributed equally to this work with: Nikolai N. Khodarev, Paul Roach

Current address: Department of Surgery, Naval Medical Center, Portsmouth, Virginia, United States of America

Affiliation Department of Surgery, University of Chicago, Chicago, Illinois, United States of America
⨯
Sean P. Pitroda,

Affiliation Department of Radiation and Cellular Oncology, University of Chicago, Chicago, Illinois, United States of America
⨯
Daniel W. Golden,

Affiliation Department of Radiation and Cellular Oncology, University of Chicago, Chicago, Illinois, United States of America
⨯
Mihir Bhayani,

Affiliation Department of Surgery, University of Chicago, Chicago, Illinois, United States of America
⨯
Michael Y. Shao,

Affiliation Department of Surgery, University of Chicago, Chicago, Illinois, United States of America
⨯
Thomas E. Darga,

Affiliation Department of Radiation and Cellular Oncology, University of Chicago, Chicago, Illinois, United States of America
⨯
Mara G. Beveridge,

Affiliation Department of Radiation and Cellular Oncology, University of Chicago, Chicago, Illinois, United States of America
⨯
Ravi F. Sood,

Affiliation Department of Radiation and Cellular Oncology, University of Chicago, Chicago, Illinois, United States of America
⨯
Harold G. Sutton,

Affiliation Department of Radiation and Cellular Oncology, University of Chicago, Chicago, Illinois, United States of America
⨯
Michael A. Beckett,

Affiliation Department of Radiation and Cellular Oncology, University of Chicago, Chicago, Illinois, United States of America
⨯
Helena J. Mauceri,

Affiliation Department of Radiation and Cellular Oncology, University of Chicago, Chicago, Illinois, United States of America
⨯
Mitchell C. Posner,

Affiliation Department of Surgery, University of Chicago, Chicago, Illinois, United States of America
⨯
Ralph R. Weichselbaum

* E-mail: rrw@radonc.uchicago.edu

Affiliation Department of Radiation and Cellular Oncology, University of Chicago, Chicago, Illinois, United States of America
⨯

STAT1 Pathway Mediates Amplification of Metastatic Potential and Resistance to Therapy

Nikolai N. Khodarev,
Paul Roach,
Sean P. Pitroda,
Daniel W. Golden,
Mihir Bhayani,
Michael Y. Shao,
Thomas E. Darga,
Mara G. Beveridge,
Ravi F. Sood,
Harold G. Sutton

Published: June 8, 2009
https://doi.org/10.1371/journal.pone.0005821

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