BH3 Peptides Induce Mitochondrial Fission and Cell Death Independent of BAX/BAK

Emelyn H. Shroff; Colleen M. Snyder; G. R. Scott Budinger; Manu Jain; Teng-Leong Chew; Satya Khuon; Harris Perlman; Navdeep S. Chandel

doi:10.1371/journal.pone.0005646

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Peer-reviewed

Research Article

BH3 Peptides Induce Mitochondrial Fission and Cell Death Independent of BAX/BAK

Emelyn H. Shroff,

Affiliation Department of Medicine, Northwestern University Medical School, Chicago, Illinois, United States of America
⨯
Colleen M. Snyder,

Affiliation Department of Medicine, Northwestern University Medical School, Chicago, Illinois, United States of America
⨯
G. R. Scott Budinger,

Affiliations Department of Medicine, Northwestern University Medical School, Chicago, Illinois, United States of America, Department of Cell and Molecular Biology Northwestern University Medical School, Chicago, Illinois, United States of America
⨯
Manu Jain,

Affiliations Department of Medicine, Northwestern University Medical School, Chicago, Illinois, United States of America, Department of Cell and Molecular Biology Northwestern University Medical School, Chicago, Illinois, United States of America
⨯
Teng-Leong Chew,

Affiliations Cell imaging facility, Northwestern University Medical School, Chicago, Illinois, United States of America, Department of Cell and Molecular Biology Northwestern University Medical School, Chicago, Illinois, United States of America
⨯
Satya Khuon,

Affiliations Cell imaging facility, Northwestern University Medical School, Chicago, Illinois, United States of America, Department of Cell and Molecular Biology Northwestern University Medical School, Chicago, Illinois, United States of America
⨯
Harris Perlman,

Affiliation Department of Medicine, Northwestern University Medical School, Chicago, Illinois, United States of America
⨯
Navdeep S. Chandel

* E-mail: nav@northwestern.edu

Affiliations Department of Medicine, Northwestern University Medical School, Chicago, Illinois, United States of America, Department of Cell and Molecular Biology Northwestern University Medical School, Chicago, Illinois, United States of America
⨯

BH3 Peptides Induce Mitochondrial Fission and Cell Death Independent of BAX/BAK

Emelyn H. Shroff,
Colleen M. Snyder,
G. R. Scott Budinger,
Manu Jain,
Teng-Leong Chew,
Satya Khuon,
Harris Perlman,
Navdeep S. Chandel

Published: May 21, 2009
https://doi.org/10.1371/journal.pone.0005646

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Mitochondria
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Cell death
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Apoptosis
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Mitochondrial membrane
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Autophagic cell death
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DNA-binding proteins
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Membrane potential
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