Overexpression of the Mitochondrial T3 Receptor Induces Skeletal Muscle Atrophy during Aging

François Casas; Laurence Pessemesse; Stéphanie Grandemange; Pascal Seyer; Olivier Baris; Naïg Gueguen; Christelle Ramonatxo; Florence Perrin; Gilles Fouret; Laurence Lepourry; Gérard Cabello; Chantal Wrutniak-Cabello

doi:10.1371/journal.pone.0005631

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Open Access

Peer-reviewed

Research Article

Overexpression of the Mitochondrial T3 Receptor Induces Skeletal Muscle Atrophy during Aging

François Casas ,

* E-mail: casasf@supagro.inra.fr

Affiliations INRA, UMR866 Différenciation cellulaire et croissance, Montpellier, France, Université Montpellier I et II, Montpellier, France
⨯
Laurence Pessemesse,

Affiliations INRA, UMR866 Différenciation cellulaire et croissance, Montpellier, France, Université Montpellier I et II, Montpellier, France
⨯
Stéphanie Grandemange,

Affiliations INRA, UMR866 Différenciation cellulaire et croissance, Montpellier, France, Université Montpellier I et II, Montpellier, France
⨯
Pascal Seyer,

Affiliations INRA, UMR866 Différenciation cellulaire et croissance, Montpellier, France, Université Montpellier I et II, Montpellier, France
⨯
Olivier Baris,

Affiliations INRA, UMR866 Différenciation cellulaire et croissance, Montpellier, France, Université Montpellier I et II, Montpellier, France
⨯
Naïg Gueguen,

Affiliations INRA, UMR866 Différenciation cellulaire et croissance, Montpellier, France, Université Montpellier I et II, Montpellier, France
⨯
Christelle Ramonatxo,

Affiliations INRA, UMR866 Différenciation cellulaire et croissance, Montpellier, France, Université Montpellier I et II, Montpellier, France
⨯
Florence Perrin,

Affiliation INSERM, U583 Institut des Neurosciences de Montpellier, Université Montpellier I et II, Montpellier, France
⨯
Gilles Fouret,

Affiliations INRA, UMR866 Différenciation cellulaire et croissance, Montpellier, France, Université Montpellier I et II, Montpellier, France
⨯
Laurence Lepourry,

Affiliations INRA, UMR866 Différenciation cellulaire et croissance, Montpellier, France, Université Montpellier I et II, Montpellier, France
⨯
Gérard Cabello,

Affiliations INRA, UMR866 Différenciation cellulaire et croissance, Montpellier, France, Université Montpellier I et II, Montpellier, France
⨯
Chantal Wrutniak-Cabello

Affiliations INRA, UMR866 Différenciation cellulaire et croissance, Montpellier, France, Université Montpellier I et II, Montpellier, France
⨯

Overexpression of the Mitochondrial T3 Receptor Induces Skeletal Muscle Atrophy during Aging

François Casas,
Laurence Pessemesse,
Stéphanie Grandemange,
Pascal Seyer,
Olivier Baris,
Naïg Gueguen,
Christelle Ramonatxo,
Florence Perrin,
Gilles Fouret,
Laurence Lepourry

Published: May 20, 2009
https://doi.org/10.1371/journal.pone.0005631

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Mitochondria
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Mouse models
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Genetically modified animals
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Hyperexpression techniques
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Muscle proteins
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Skeletal muscles
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Oxidative stress
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Mitochondrial DNA
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