Misbehaviour of XIST RNA in Breast Cancer Cells

Silvia M. Sirchia; Silvia Tabano; Laura Monti; Maria P. Recalcati; Manuela Gariboldi; Francesca R. Grati; Giovanni Porta; Palma Finelli; Paolo Radice; Monica Miozzo

doi:10.1371/journal.pone.0005559

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Open Access

Peer-reviewed

Research Article

Misbehaviour of XIST RNA in Breast Cancer Cells

Silvia M. Sirchia ,

* E-mail: silvia.sirchia@unimi.it

Affiliation Department of Medicine, Surgery and Dentistry, Medical Genetics Unit, Università degli Studi di Milano, Milano, Italy
⨯
Silvia Tabano,

Affiliation Department of Medicine, Surgery and Dentistry, Medical Genetics Unit, Università degli Studi di Milano, Milano, Italy
⨯
Laura Monti,

Affiliation Department of Medicine, Surgery and Dentistry, Medical Genetics Unit, Università degli Studi di Milano, Milano, Italy
⨯
Maria P. Recalcati,

Affiliation Laboratory of Medical Cytogenetics and Molecular Genetics, Istituto Auxologico Italiano, Milano, Italy
⨯
Manuela Gariboldi,

Affiliations IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milano, Italy, Department of Experimental Oncology , Fondazione IRCCS Istituto Nazionale Tumori, Milano, Italy
⨯
Francesca R. Grati,

Affiliation Cytogenetics and Molecular Biology Unit, Laboratorio TOMA, Varese, Italy
⨯
Giovanni Porta,

Affiliation Department of Experimental and Clinical Biomedical Sciences, Università dell'Insubria, Varese, Italy
⨯
Palma Finelli,

Affiliations Laboratory of Medical Cytogenetics and Molecular Genetics, Istituto Auxologico Italiano, Milano, Italy, Department of Biology and Genetics for Medical Sciences, Università degli Studi di Milano, Milano, Italy
⨯
Paolo Radice,

Affiliations IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milano, Italy, Department of Experimental Oncology , Fondazione IRCCS Istituto Nazionale Tumori, Milano, Italy
⨯
Monica Miozzo

Affiliation Department of Medicine, Surgery and Dentistry, Medical Genetics Unit, Università degli Studi di Milano, Milano, Italy
⨯

Misbehaviour of XIST RNA in Breast Cancer Cells

Silvia M. Sirchia,
Silvia Tabano,
Laura Monti,
Maria P. Recalcati,
Manuela Gariboldi,
Francesca R. Grati,
Giovanni Porta,
Palma Finelli,
Paolo Radice,
Monica Miozzo

Published: May 15, 2009
https://doi.org/10.1371/journal.pone.0005559

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Genetic causes of cancer
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X chromosome inactivation
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Small interfering RNA
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Breast cancer
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DNA methylation
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Heterochromatin
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Fluorescent in situ hybridization
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X chromosomes
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