Both Strands of siRNA Have Potential to Guide Posttranscriptional Gene Silencing in Mammalian Cells

Jun-Xia Wei; Jie Yang; Ji-Feng Sun; Lin-Tao Jia; Yong Zhang; Hui-Zhong Zhang; Xia Li; Yan-Ling Meng; Li-Bo Yao; An-Gang Yang

doi:10.1371/journal.pone.0005382

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Open Access

Peer-reviewed

Research Article

Both Strands of siRNA Have Potential to Guide Posttranscriptional Gene Silencing in Mammalian Cells

Jun-Xia Wei ,

Contributed equally to this work with: Jun-Xia Wei, Jie Yang, Ji-Feng Sun

Affiliations State Key Laboratory of Cancer Biology; Department of Biochemistry and Molecular Biology, Fourth Military Medical University, Xi'an, China, Department of Clinical Diagnosis, Tangdu Hospital, Fourth Military Medical University, Xi'an, China
⨯
Jie Yang ,

Contributed equally to this work with: Jun-Xia Wei, Jie Yang, Ji-Feng Sun

Affiliations State Key Laboratory of Cancer Biology; Department of Biochemistry and Molecular Biology, Fourth Military Medical University, Xi'an, China, Department of Nephrology, Tangdu Hospital, Fourth Military Medical University, Xi'an, China
⨯
Ji-Feng Sun ,

Contributed equally to this work with: Jun-Xia Wei, Jie Yang, Ji-Feng Sun

Affiliation Department of Nephrology, Tangdu Hospital, Fourth Military Medical University, Xi'an, China
⨯
Lin-Tao Jia,

Affiliation State Key Laboratory of Cancer Biology; Department of Biochemistry and Molecular Biology, Fourth Military Medical University, Xi'an, China
⨯
Yong Zhang,

Affiliation Department of Immunology, Fourth Military Medical University, Xi'an, China
⨯
Hui-Zhong Zhang,

Affiliation Department of Clinical Diagnosis, Tangdu Hospital, Fourth Military Medical University, Xi'an, China
⨯
Xia Li,

Affiliation State Key Laboratory of Cancer Biology; Department of Biochemistry and Molecular Biology, Fourth Military Medical University, Xi'an, China
⨯
Yan-Ling Meng,

Affiliation Department of Immunology, Fourth Military Medical University, Xi'an, China
⨯
Li-Bo Yao,

Affiliation State Key Laboratory of Cancer Biology; Department of Biochemistry and Molecular Biology, Fourth Military Medical University, Xi'an, China
⨯
An-Gang Yang

* E-mail: agyang@fmmu.edu.cn

Affiliations State Key Laboratory of Cancer Biology; Department of Biochemistry and Molecular Biology, Fourth Military Medical University, Xi'an, China, Department of Immunology, Fourth Military Medical University, Xi'an, China
⨯

Both Strands of siRNA Have Potential to Guide Posttranscriptional Gene Silencing in Mammalian Cells

Jun-Xia Wei,
Jie Yang,
Ji-Feng Sun,
Lin-Tao Jia,
Yong Zhang,
Hui-Zhong Zhang,
Xia Li,
Yan-Ling Meng,
Li-Bo Yao,
An-Gang Yang

Published: April 29, 2009
https://doi.org/10.1371/journal.pone.0005382

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